Evidence map›Paper›PMID 27503638›Full record

ArticleAntimicrobial agents and chemotherapy2016

High Prevalence of Carbapenemase-Producing Enterobacteriaceae among Hospitalized Children in Luanda, Angola.

Nicolas Kieffer, Patrice Nordmann, Marta Aires-de-Sousa, Laurent Poirel

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Multidrug-Resistant and Potentially PathogenicFoods (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Faecal Carriage of Multidrug ResistantThe East African health research journal · 2024
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Characterization of the First Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2022
    Article
  18. Persistence and Dissemination Capacities of aAntibiotics (Basel, Switzerland) · 2022
    Article
  19. Article
  20. Multidrug-Resistant and Carbapenemase-ProducingBioMed research international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Nicolas KiefferEmerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland INSERM European Unit (LEA, Paris, France), University of Fribourg, Fribourg, Switzerland.
Patrice NordmannEmerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland INSERM European Unit (LEA, Paris, France), University of Fribourg, Fribourg, Switzerland University of Lausanne and University Hospital Center, Lausanne, Switzerland.
Marta Aires-de-SousaEscola Superior de Saúde da Cruz Vermelha Portuguesa (ESSCVP), Lisbon, Portugal.
Laurent PoirelEmerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland INSERM European Unit (LEA, Paris, France), University of Fribourg, Fribourg, Switzerland laurent.poirel@unifr.ch.
Inserm · FREscola Superior de Saúde da Cruz Vermelha Portuguesa · PTUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the prevalence of carbapenemase-producing Enterobacteriaceae in Luanda, Angola. A total of 157 rectal samples were collected from children visiting a pediatric hospital in Luanda in March 2015. Fifty-seven imipenem-nonsusceptible enterobacterial isolates were recovered, most of which were non-clonally related. The blaOXA-181 (50/57) and blaNDM-1 (7/57) carbapenemase genes were identified. Notably, OXA-181-producing Escherichia coli isolates rarely coproduced extended-spectrum β-lactamases and consequently remained susceptible to broad-spectrum cephalosporins. The blaOXA-181 gene was always located on an IncX3 plasmid, while the blaNDM-1 gene was located on either IncFIA or IncA/C plasmids. The study identified a high prevalence of OXA-181 among hospitalized children in Angola.

Indexed as

AdolescentAngolaBacterial Proteinsbeta-LactamasesChildChild, PreschoolElectrophoresis, Gel, Pulsed-FieldEnterobacteriaceaeEnterobacteriaceae InfectionsEscherichia coli ProteinsFecesHospitalsHumansInfantBacterial Proteinsbeta-lactamase NDM-1beta-lactamase OXA-181, E colibeta-LactamasescarbapenemaseEscherichia coli Proteins

Identifiers

PMID27503638
PMCPMC5038229
OpenAlexW2522807597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.