Trial reportDysphagia2016
A Comparative Study Between Two Sensory Stimulation Strategies After Two Weeks Treatment on Older Patients with Oropharyngeal Dysphagia.
Trial report in Dysphagia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 5 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Review of the effectiveness of neuromuscular electrical stimulation in the treatment of dysphagia - an update.German medical science : GMS e-journal · 2022Pooled it
- Transcutaneous electrical nerve stimulation in speech therapy rehabilitation of voice and swallowing function in adults-a systematic review.Clinical and experimental dental research · 2021Pooled it
- Effect of TRP-Stimulating Compounds to Reduce Swallowing Response Time in the Elderly: A Systematic Review.Dysphagia · 2021Pooled it
- Pooled it
- Swallowing therapy for dysphagia in acute and subacute stroke.The Cochrane database of systematic reviews · 2018Pooled it
- An oral nutritional supplement with TRPM8 agonists as a cooling flavor improved swallowing function in post-stroke patients with oropharyngeal dysphagia.Scientific reports · 2026Trial
- Transcutaneous electrical stimulation in chronic post-stroke oropharyngeal dysphagia: pooled biomechanical and kinematic analysis from a one-year randomized controlled clinical trial.Scientific reports · 2025Trial
- Cervical percutaneous interferential current stimulation improves citric acid cough tests in patients with Parkinson's disease on medication.Scientific reports · 2024Trial
- Effect of a gum-based thickener on the safety of swallowing in patients with poststroke oropharyngeal dysphagia.Neurogastroenterology and motility · 2019Trial
- Interferential current sensory stimulation, through the neck skin, improves airway defense and oral nutrition intake in patients with dysphagia: a double-blind randomized controlled trial.Clinical interventions in aging · 2017Trial
- [Oropharyngeal dysphagia as a neurogeriatric syndrome].Zeitschrift fur Gerontologie und Geriatrie · 2026Review
- Review
- Effects of speech therapy with or without transcutaneous electrical stimulation on patients with vocal cord paralysis after thoracic surgery.Journal of thoracic disease · 2025Article
- Topical ATP Application in the Peripheral Swallowing-Related Regions Facilitates Triggering of the Swallowing Reflex Involving P2X3 Receptors.Function (Oxford, England) · 2025Article
- The effects of simulated gastroesophageal reflux on infant pig oropharyngeal feeding physiology.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Treatment of Post-stroke Dysphagia With Interferential Current: Three Case Reports and a Review of the Literature.Cureus · 2024Article
- The importance of taste on swallowing function.Frontiers in nutrition · 2024Review
- Complications of oropharyngeal dysphagia in older individuals and patients with neurological disorders: insights from Mataró hospital, Catalonia, Spain.Frontiers in neurology · 2024Article
- Transient receptor potential channels as an emerging therapeutic target for oropharyngeal dysphagia.The Japanese dental science review · 2023Review
- Gustatory stimulus interventions for older adults with dysphagia: a scoping review.Aging clinical and experimental research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oropharyngeal dysphagia (OD) is a prevalent geriatric syndrome. Treatment is based on compensatory strategies to avoid complications. New treatments based on sensory stimulation to promote the recovery of the swallowing function have proved effective in acute studies but prolonged treatment needs further research. Our aim was to evaluate and compare the effect of two, longer-term sensory treatment strategies on older patients with OD. 38 older patients (≥70 years) were studied with videofluoroscopy (pre/posttreatment) and randomized into two 10-day treatment groups: Group A-transient receptor potential vanilloid 1 (TRPV1) agonist (capsaicin 1 × 10(-5) M) and Group B-transcutaneous sensory electrical stimulation (TSES) (Intelect VitalStim, biphasic pulses, 300 μs, 80 Hz). Patients were analyzed for treatment response. Patients were old (80.47 ± 5.2 years), with comorbidities (3.11 ± 1.59 Charlson Index), polymedication (8.92 ± 3.31 drugs/patient), and mild functional impairment (86.84 ± 17.84 Barthel Index), and 28.9 % were at risk of malnutrition (MNA-sf). Overall, all patients had videofluoroscopic signs of impaired safety of swallow (ISS) with delayed oropharyngeal swallow response (OSR). After sensory stimulation, prevalence of ISS decreased to 68.42 % in both groups (P = 0.019). There were 68.42 % responders in Group A (TRPV1) and 42.11 % in Group B (TSES). Group A responders showed an improvement in the penetration-aspiration scale (PAS, 5.23 ± 2.04 to 3 ± 1.47; P = 0.002), and the same was true for those of Group B (4.63 ± 1.41 to 2.13 ± 0.64; P = 0.007). 10-day sensory stimulation with either therapy improved safety of swallow and OSR in older patients with OD, reducing the severity of OD in a significant subgroup of these patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.