Evidence map›Paper›PMID 27503554›Full record

ArticleEuropean journal of nutrition2017

Estimating safe maximum levels of vitamins and minerals in fortified foods and food supplements.

Albert Flynn, Laura Kehoe, Áine Hennessy, Janette Walton

Abstract read
In one paragraph

Article in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Vitamin BMolecules (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Albert FlynnSchool of Food and Nutritional Sciences, University College Cork, Cork, Ireland. a.flynn@ucc.ie.ORCID http://orcid.org/0000-0002-7072-4202
Laura KehoeSchool of Food and Nutritional Sciences, University College Cork, Cork, Ireland.
Áine HennessySchool of Food and Nutritional Sciences, University College Cork, Cork, Ireland.
Janette WaltonSchool of Food and Nutritional Sciences, University College Cork, Cork, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo show how safe maximum levels (SML) of vitamins and minerals in fortified foods and supplements may be estimated in population subgroups.

methodsSML were estimated for adults and 7- to 10-year-old children for six nutrients (retinol, vitamins B6, D and E, folic acid, iron and calcium) using data on usual daily nutrient intakes from Irish national nutrition surveys.

resultsSML of nutrients in supplements were lower for children than for adults, except for calcium and iron. Daily energy intake from fortified foods in high consumers (95th percentile) varied by nutrient from 138 to 342 kcal in adults and 40-309 kcal in children. SML (/100 kcal) of nutrients in fortified food were lower for children than adults for vitamins B6 and D, higher for vitamin E, with little difference for other nutrients. Including 25 % 'overage' for nutrients in fortified foods and supplements had little effect on SML. Nutritionally significant amounts of these nutrients can be added safely to supplements and fortified foods for these population subgroups. The estimated SML of nutrients in fortified foods and supplements may be considered safe for these population subgroups over the long term given the food composition and dietary patterns prevailing in the respective dietary surveys.

conclusionsThis risk assessment approach shows how nutrient intake data may be used to estimate, for population subgroups, the SML for vitamins and minerals in both fortified foods and supplements, separately, each taking into account the intake from other dietary sources.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolDietary SupplementsFemaleFood AnalysisFood, FortifiedHumansMaleMiddle AgedNutrition SurveysRecommended Dietary AllowancesRisk AssessmentTrace ElementsVitaminsFortified foodsIrish national nutrition surveysMineralsSafe maximum levelsSupplementsVitamins

Identifiers

PMID27503554
PMCPMC5682849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.