ArticleAfrican journal of paediatric surgery : AJPS
Physiological marker and surgical ligation of patent ductus arteriosus in neonates.
Article in African journal of paediatric surgery : AJPS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 5 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn preterm infants, immediate complications of surgical closure of a patent ductus arteriosus (PDA) are often serious and due to haemorrhage or ligation of incorrect structures. The aim of this study was to measure blood pressure (BP) changes during ligation and hence introduce a novel physiological marker to alert surgeons to the ligation of incorrect structures. MATERIALS AND
methodsThis study included 146 preterm babies (≤35 weeks of gestation) who underwent surgical PDA closure of a left-to-right unidirectional PDA between June 2006 and December 2015. The median weight was 920 g (range, from 520 to 2200 g). In all cases, the PDA was test cross-clamped, and the lower limb or umbilical artery BP was recorded before ligation.
resultsBased on preoperative echocardiography, the PDA diameter range was 2-4 mm in 135 cases and 5-6 mm in 11 cases. During test clamping of the PDA, a 20-60% rise in mean BP was recorded. The lower figure was observed with smaller PDAs.
conclusionIt is estimated that the mean BP should rise by 10% for every mm of PDA diameter during test clamping and ligation of the PDA, irrespective of weight or age. The absence of this expected rise in mean BP indicates that an incorrect structure might have been clamped.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.