Evidence map›Paper›PMID 27502776›Full record

Trial reportBMC infectious diseases2016

Evaluation of a demand-creation intervention for couples' HIV testing services among married or cohabiting individuals in Rakai, Uganda: a cluster-randomized intervention trial.

Joseph K B Matovu, Jim Todd, Rhoda K Wanyenze, Robert Kairania, David Serwadda, Fred Wabwire-Mangen

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02492061 (Demand Creation for Couples' HIV Counseling and Testing, Linkage to and Retention in HIV Care Among Married Couples in Rakai, Uganda), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02492061 naunknown statusnot on this map

Demand Creation for Couples' HIV Counseling and Testing, Linkage to and Retention in HIV Care Among Married Couples in Rakai, Uganda

TypeinterventionalSponsorMakerere UniversityRan2013 to 2015Enrolled3,076ConditionsHIV/AIDSArmsDemand creation for couples' HCT
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Results of a Couples-Based Randomized Controlled Trial Aimed to Increase Testing for HIV.Journal of acquired immune deficiency syndromes (1999) · 2019
    Trial
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph K B MatovuDepartment of Community Health and Behavioral Sciences, Makerere University College of Health Sciences, School of Public Health, Kampala, Uganda. jmatovu@musph.ac.ug.
Jim ToddDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Rhoda K WanyenzeDepartment of Disease Control and Environmental Health, Makerere University College of Health Sciences, School of Public Health, Kampala, Uganda.
Robert KairaniaRakai Health Sciences Program/Uganda Virus Research Institute, Kalisizo, Uganda.
David SerwaddaDepartment of Disease Control and Environmental Health, Makerere University College of Health Sciences, School of Public Health, Kampala, Uganda.
Fred Wabwire-MangenRegional Center for Quality of Health Care, Makerere University College of Health Sciences, School of Public Health, Kampala, Uganda.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundUptake of couples' HIV counseling and testing (couples' HCT) services remains largely low in most settings. We report the effect of a demand-creation intervention trial on couples' HCT uptake among married or cohabiting individuals who had never received couples' HCT.

methodsThis was a cluster-randomized intervention trial implemented in three study regions with differing HIV prevalence levels (range: 9-43 %) in Rakai district, southwestern Uganda, between February and September 2014. We randomly assigned six clusters (1:1) to receive the intervention or serve as the comparison arm using computer-generated random numbers. In the intervention clusters, individuals attended small group, couple and male-focused interactive sessions, reinforced with testimonies from 'expert couples', and received invitation coupons to test together with their partners at designated health facilities. In the comparison clusters, participants attended general adult health education sessions but received no invitation coupons. The primary outcome was couples' HCT uptake, measured 12 months post-baseline. Baseline data were collected between November 2013 and February 2014 while follow-up data were collected between March and April 2015. We conducted intention-to-treat analysis using a mixed effects Poisson regression model to assess for differences in couples' HCT uptake between the intervention and comparison clusters. Data analysis was conducted using STATA statistical software, version 14.1.

resultsOf 2135 married or cohabiting individuals interviewed at baseline, 42 % (n = 846) had ever received couples' HCT. Of those who had never received couples' HCT (n = 1,174), 697 were interviewed in the intervention clusters while 477 were interviewed in the comparison clusters. 73.6 % (n = 513) of those interviewed in the intervention and 82.6 % (n = 394) of those interviewed in the comparison cluster were interviewed at follow-up. Of those interviewed, 72.3 % (n = 371) in the intervention and 65.2 % (n = 257) in the comparison clusters received HCT. Couples' HCT uptake was higher in the intervention than in the comparison clusters (20.3 % versus 13.7 %; adjusted prevalence ratio (aPR) = 1.43, 95 % CI: 1.02, 2.01, P = 0.04).

conclusionOur findings show that a small group, couple and male-focused, demand-creation intervention reinforced with testimonies from 'expert couples', improved uptake of couples' HCT in this rural setting.

trial registrationClinicalTrials.gov, NCT02492061 . Date of registration: June 14, 2015.

Indexed as

CounselingHealth BehaviorSexual PartnersSpousesAdolescentAdultFamily CharacteristicsFemaleHealth PromotionHIV InfectionsHumansMaleMass ScreeningMiddle AgedPrevalenceRegression AnalysisCouples’ HCTDemand creationInterventionRakaiUgandaUptake

Identifiers

PMID27502776
PMCPMC4977664

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.