ArticleeLife2016
A circuit motif in the zebrafish hindbrain for a two alternative behavioral choice to turn left or right.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 86 citations in OpenAlex.
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- Thalamic regulation of a visual critical period and motor behavior.Cell reports · 2023Article
- Visual object detection biases escape trajectories following acoustic startle in larval zebrafish.Current biology : CB · 2022Article
- Whole-brain optical access in a small adult vertebrate with two- and three-photon microscopy.iScience · 2022Article
- Organization of the gravity-sensing system in zebrafish.Nature communications · 2022Article
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Corrections and comments
- Commented on byA choice motif.2016
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Animals collect sensory information from the world and make adaptive choices about how to respond to it. Here, we reveal a network motif in the brain for one of the most fundamental behavioral choices made by bilaterally symmetric animals: whether to respond to a sensory stimulus by moving to the left or to the right. We define network connectivity in the hindbrain important for the lateralized escape behavior of zebrafish and then test the role of neurons by using laser ablations and behavioral studies. Key inhibitory neurons in the circuit lie in a column of morphologically similar cells that is one of a series of such columns that form a developmental and functional ground plan for building hindbrain networks. Repetition within the columns of the network motif we defined may therefore lie at the foundation of other lateralized behavioral choices.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.