ArticlePlant cell reports2016
Papaya CpERF9 acts as a transcriptional repressor of cell-wall-modifying genes CpPME1/2 and CpPG5 involved in fruit ripening.
Article in Plant cell reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 82 citations in OpenAlex.
- FcMAPK4-phosphorylated FcNOR activates FcERF5 to promote fig fruit softening through activation of FcPG12 expression.Journal of integrative plant biology · 2026Article
- CpERF-WRI1 Manipulates Ethylene Sensing by Regulating the Expression of CpERS1 and Fruit Ripening in Papaya.Plant biotechnology journal · 2026Article
- Molecular Module FcERF71-FcDREB1 of Fig Represses Fruit Softening viaJournal of agricultural and food chemistry · 2026Article
- Genome-Wide Identification and Functional Analysis ofPlants (Basel, Switzerland) · 2025Article
- Detection of Ethylene Signaling Using Bioinformatics Tools in Plants.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Promoter variations of ClERF1 gene determines flesh firmness in watermelon.BMC plant biology · 2024Article
- Banana MabHLH28 positively regulates the expression of softening-related genes to mediate fruit ripening independently or via cooperating with MaWRKY49/111.Horticulture research · 2024Article
- Genome-wide identification of MAPK family in papaya (Carica papaya) and their involvement in fruit postharvest ripening.BMC plant biology · 2024Article
- Polygalacturonase gene family analysis identifies FcPG12 as a key player in fig (Ficus carica L.) fruit softening.BMC plant biology · 2023Article
- The transcription factor CmERFI-2 represses CmMYB44 expression to increase sucrose levels in oriental melon fruit.Plant physiology · 2023Article
- Promoter Variation of the Key Apple Fruit Texture Related GenePlants (Basel, Switzerland) · 2023Article
- Ethylene Response Factor MaERF012 Modulates Fruit Ripening by Regulating Chlorophyll Degradation and Softening in Banana.Foods (Basel, Switzerland) · 2022Article
- Abscisic acid-responsive transcription factors PavDof2/6/15 mediate fruit softening in sweet cherry.Plant physiology · 2022Article
- Molecular and Genetic Events Determining the Softening of Fleshy Fruits: A Comprehensive Review.International journal of molecular sciences · 2022Review
- APETALA2/ethylene responsive factor in fruit ripening: Roles, interactions and expression regulation.Frontiers in plant science · 2022Review
- Quantitative Ubiquitylomic Analysis of the Dynamic Changes and Extensive Modulation of Ubiquitylation in Papaya During the Fruit Ripening Process.Frontiers in plant science · 2022Article
- Article
- Transcriptomic and physiological analysis reveals the possible mechanism of ultrasound inhibiting strawberry (Frontiers in nutrition · 2022Article
- The NAM/ATAF1/2/CUC2 transcription factor PpNAC.A59 enhances PpERF.A16 expression to promote ethylene biosynthesis during peach fruit ripening.Horticulture research · 2021Article
- MicroRNAs and Transcripts Associated with an Early Ripening Mutant of Pomelo (International journal of molecular sciences · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageCpERF9 controls papaya fruit ripening through transcriptional repression of cell-wall-modifying genes CpPME1/2 and CpPG5 by directly binding to their promoters. Papaya fruit ripening is an intricate and highly coordinated developmental process which is controlled by the action of ethylene and expression of numerous ethylene-responsive genes. Ethylene response factors (ERFs) representing the last regulators of ethylene-signaling pathway determine the specificities of ethylene response. However, knowledge concerning the transcriptional controlling mechanism of ERF-mediated papaya fruit ripening is limited. In the present work, a gene-encoding AP2/ERF protein with two ERF-associated amphiphilic repression (EAR) motifs, named CpERF9, was characterized from papaya fruit. CpERF9 was found to localize in nucleus, and possess transcriptional repression ability. CpERF9 expression steadily decreased during papaya fruit ripening, while several genes encoding pectin methylesterases (PMEs) and polygalacturonases (PGs), such as CpPME1/2 and CpPG5, were gradually increased, paralleling the decline of fruit firmness. Electrophoretic mobility shift assay (EMSA) demonstrated a specific binding of CpERF9 to promoters of CpPME1/2 and CpPG5, via the GCC-box motif. Transient expression of CpERF9 in tobacco repressed CpPME1/2 and CpPG5 promoter activities, which was depended on two EAR motifs of CpERF9 protein. Taken together, these findings suggest that papaya CpERF9 may act as a transcriptional repressor of several cell-wall modifying genes, such as CpPME1/2 and CpPG5, via directly binding to their promoters.
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