Evidence map›Paper›PMID 27502542›Full record

ArticleScientific reports2016

Calpains are involved in asexual and sexual development, cell wall integrity and pathogenicity of the rice blast fungus.

Xiao-Hong Liu, Guo-Ao Ning, Lu-Yao Huang, Ya-Hui Zhao, Bo Dong, Jian-Ping Lu, Fu-Cheng Lin

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Journal of fungi (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xiao-Hong LiuState Key Laboratory for Rice Biology, Biotechnology Institute, Zhejiang University, Hangzhou 310058, Zhejiang Province, China.
Guo-Ao NingState Key Laboratory for Rice Biology, Biotechnology Institute, Zhejiang University, Hangzhou 310058, Zhejiang Province, China.
Lu-Yao HuangState Key Laboratory for Rice Biology, Biotechnology Institute, Zhejiang University, Hangzhou 310058, Zhejiang Province, China.
Ya-Hui ZhaoState Key Laboratory for Rice Biology, Biotechnology Institute, Zhejiang University, Hangzhou 310058, Zhejiang Province, China.
Bo DongState Key Laboratory of Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, Zhejiang Province, China.
Jian-Ping LuCollege of Life Sciences, Zhejiang University, Hangzhou 310058, Zhejiang Province, China.
Fu-Cheng LinState Key Laboratory for Rice Biology, Biotechnology Institute, Zhejiang University, Hangzhou 310058, Zhejiang Province, China.
Zhejiang University · CNChina National Rice Research Institute · CNZheJiang Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calpains are ubiquitous and well-conserved proteins that belong to the calcium-dependent, non-lysosomal cysteine protease family. In this study, 8 putative calpains were identified using Pfam domain analysis and BlastP searches in M. oryzae. Three single gene deletion mutants (ΔMocapn7, ΔMocapn9 and ΔMocapn14) and two double gene deletion mutants (ΔMocapn4ΔMocapn7 and ΔMocapn9ΔMocapn7) were obtained using the high-throughput gene knockout system. The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the ΔMocapn7, ΔMocapn4ΔMocapn7 and ΔMocapn9ΔMocapn7 mutants showed reduced pathogenicity on rice and barley.

Indexed as

CalpainCell WallFungal ProteinsGene DeletionGene Expression ProfilingGene Expression Regulation, FungalHordeumMagnaportheModels, GeneticMutationMyceliumOryzaPlant DiseasesProteomeSpores, FungalVirulenceCalpainFungal ProteinsProteome

Identifiers

PMID27502542
PMCPMC4977516
OpenAlexW2490709606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.