ReviewParasites & vectors2016
Systemically and cutaneously distributed ectoparasiticides: a review of the efficacy against ticks and fleas on dogs.
Review in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 86 citations in OpenAlex.
- Development and Validation of LC-MS/MS Methods for Quantification of Fluralaner and Moxidectin in Cat Plasma and Its Application in a Pharmacokinetic Study.Animals : an open access journal from MDPI · 2026Article
- Why are the ticks winning, and what can we do about it?Ticks and tick-borne diseases · 2026Review
- Human-animal relationships in older persons: from pet companionship to animal-assisted interventions. A position statement.Aging clinical and experimental research · 2026Review
- Essential Oils for Flea and Tick Control in Companion Animals: A Critical Review of Efficacy, Safety, Resistance Mitigation and Integrated Pest Management.Antibiotics (Basel, Switzerland) · 2026Review
- Evaluation of efficacy and pharmacokinetics of novel fluralaner tablet formulation (WellPet™) in dogs.Frontiers in veterinary science · 2026Article
- Semi-field evaluation of efficacy and residual activity of a microencapsulated pyriproxyfen formulation onMalariaWorld journal · 2026Article
- Environmental Risks and Toxicity of Fipronil and Imidacloprid Used in Pets Ectoparasiticides.Animals : an open access journal from MDPI · 2025Article
- Unwanted souvenirs-import routes and pathogen detection of the non-endemic tick Rhipicephalus sanguineus s.l. in Germany.Experimental & applied acarology · 2025Article
- Tick Control Strategies: Critical Insights into Chemical, Biological, Physical, and Integrated Approaches for Effective Hard Tick Management.Veterinary sciences · 2025Review
- Efficacy of monthly treatment with oral fluralaner (BravectoParasites & vectors · 2024Article
- Assessment of the in vitro acaricidal activity of BravectoParasites & vectors · 2024Article
- Comparative Evaluation of the Efficacy of Two Ectoparasiticides in Preventing the Acquisition ofMicroorganisms · 2024Article
- Prevalence, clinical presentation, and therapeutic outcome of ectoparasitic infestations in dogs in Egypt.Open veterinary journal · 2023Article
- Comparison of the initial and residual speed of Ixodes scapularis kill on dogs treated with a single dose of BravectoParasites & vectors · 2023Article
- Efficacy of either orally administered fluralaner or topically administered imidacloprid/flumethrin for controlling Rhipicephalus sanguineus sensu lato premises infestations.Parasites & vectors · 2023Article
- Molecular detection of pathogens from ticks collected from dogs and cats at veterinary clinics in Finland.Parasites & vectors · 2023Article
- Effectiveness of fluralaner treatment regimens for the control of canine Chagas disease: A mathematical modeling study.PLoS neglected tropical diseases · 2023Article
- Prevalence, Distribution, and Factors Associated with Vector-Borne Pathogen Infections in Pet Dogs from Different Geoclimatic Zones in Sri Lanka.Transboundary and emerging diseases · 2023Article
- Exposure of pregnant women and their children to pyrethroid insecticides in Rio de Janeiro, Brazil.Frontiers in public health · 2023Article
- One Health Approach to Tick and Tick-Borne Disease Surveillance in the United Kingdom.International journal of environmental research and public health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acaricidal (tick) and insecticidal (flea) efficacy of systemically and cutaneously distributed ectoparasiticide products for dogs are compared based on permethrin and fluralaner as representative molecules. Results of efficacy studies against fleas and ticks are reviewed that show generally good to excellent results. Both externally and systemically distributed treatments have benefits and weaknesses in potentially preventing pathogen transmission by these arthropod vectors.Four general properties are considered related to the goal of providing optimal reduction in the risk of vector-borne pathogen transmission. These are: 1. Owner adherence to the recommended treatment protocol; 2. Rapid onset of activity following administration; 3. Uniform efficacy over all areas of the treated dog at risk for parasite attachment; 4. Maintenance of high efficacy throughout the retreatment interval. In considering these four factors, a systemically distributed acaricide can offer an option that is at least as effective as a cutaneously administered acaricide with regard to the overall goal of reducing the risk of vector-borne pathogen transmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.