Evidence map›Paper›PMID 27502082›Full record

ArticleJournal of neurology2016

Relationship between type 1 metabotropic glutamate receptors and cerebellar ataxia.

Kenji Ishibashi, Yoshiharu Miura, Kinya Ishikawa, Ming-Rong Zhang, Jun Toyohara, Kiichi Ishiwata, Kenji Ishii

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
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  4. Quantitative Rodent Brain Receptor Imaging.Molecular imaging and biology · 2020
    Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kenji IshibashiResearch Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan. ishibashi@pet.tmig.or.jp.
Yoshiharu MiuraDepartment of Neurology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Kinya IshikawaDepartment of Neurology and Neurological Science, and Predictive and Preventive Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ming-Rong ZhangMolucular Probe Program, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan.
Jun ToyoharaResearch Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Kiichi IshiwataResearch Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Kenji IshiiResearch Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Tokyo Metropolitan Institute of Gerontology · JPTokyo Medical and Dental University · JPTokyo Metropolitan Komagome Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging of type 1 metabotropic glutamate receptor (mGluR1) has recently become possible using positron emission tomography (PET). We aimed to examine the relationship between mGluR1 and cerebellar ataxia. Families with spinocerebellar ataxia type 19/22 (SCA19/22) and SCA6, six patients with sporadic SCA, and 26 healthy subjects underwent PET using an mGluR1 radiotracer. Volumes-of-interest were placed on the anterior and posterior lobes and vermis. The binding potential (BP

Indexed as

AdultAgedAged, 80 and overBrainBrain MappingCalcium ChannelsCalcium Channels, N-TypeCerebellar AtaxiaFamily HealthFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedParenchymal TissueCACNA1A protein, humanCalcium ChannelsCalcium Channels, N-Typemetabotropic glutamate receptor type 1Receptors, Metabotropic Glutamate11C-ITMMPETSpinocerebellar ataxia type 19/22Spinocerebellar ataxia type 6Sporadic spinocerebellar ataxiaType 1 metabotropic glutamate receptor

Identifiers

PMID27502082
OpenAlexW2509366834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.