ArticleJournal of occupational and environmental medicine2016
Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel.
Article in Journal of occupational and environmental medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Metabolomics for exposure assessment and toxicity effects of occupational pollutants: current status and future perspectives.Metabolomics : Official journal of the Metabolomic Society · 2022Pooled it
- Investigating the Shared Mechanisms of Endocrine-Disrupting Chemicals in Urogenital Tumors.Biology · 2026Article
- Polycyclic aromatic hydrocarbon exposure in battlefield and beyond: Implications for environmental- and human health.Toxicology reports · 2026Review
- Article
- Untargeted metabolomics reveals that multiple reproductive toxicants are present at the endometrium.The Science of the total environment · 2022Article
- Utilizing a Biology-Driven Approach to Map the Exposome in Health and Disease: An Essential Investment to Drive the Next Generation of Environmental Discovery.Environmental health perspectives · 2021Article
- High-Resolution Metabolomic Assessment of Pesticide Exposure in Central Valley, California.Chemical research in toxicology · 2021Article
- Metabolome Wide Association Study of serum DDT and DDE in Pregnancy and Early Postpartum.Reproductive toxicology (Elmsford, N.Y.) · 2020Article
- High-resolution metabolomic profiling of Alzheimer's disease in plasma.Annals of clinical and translational neurology · 2020Article
- Metabolome-Wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan.Journal of occupational and environmental medicine · 2019Article
- Environmental Chemicals Altered in Association With Deployment for High Risk Areas.Journal of occupational and environmental medicine · 2019Article
- Associations of Benzo(ghi)perylene and Heptachlorodibenzo-p-dioxin in Serum of Service Personnel Deployed to Balad, Iraq, and Bagram, Afghanistan Correlates With Perturbed Amino Acid Metabolism in Human Lung Fibroblasts.Journal of occupational and environmental medicine · 2019Article
- Analysis of Postdeployment Serum Samples Identifies Potential Biomarkers of Exposure to Burn Pits and Other Environmental Hazards.Journal of occupational and environmental medicine · 2019Article
- Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Variations in Service Personnel Deployed to Balad and Bagram.Journal of occupational and environmental medicine · 2019Article
- Benzo[a]pyrene Perturbs Mitochondrial and Amino Acid Metabolism in Lung Epithelial Cells and Has Similar Correlations With Metabolic Changes in Human Serum.Journal of occupational and environmental medicine · 2019Article
- Multigenerational metabolic profiling in the Michigan PBB registry.Environmental research · 2019Article
- Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae.Biomolecules · 2018Article
- Untargeted metabolomics reveals multiple metabolites influencing smoking-related DNA methylation.Epigenomics · 2018Article
- Beyond genomics: understanding exposotypes through metabolomics.Human genomics · 2018Review
- Trends in the application of high-resolution mass spectrometry for human biomonitoring: An analytical primer to studying the environmental chemical space of the human exposome.Environment international · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
objectiveA pilot study was conducted to test the feasibility of using Department of Defense Serum Repository (DoDSR) samples to study health and exposure-related effects.
methodsThirty unidentified human serum samples were obtained from the DoDSR and analyzed for normal serum metabolites with high-resolution mass spectrometry and serum levels of free benzo(a)pyrene (BaP) by gas chromatography-mass spectrometry. Metabolic associations with BaP were determined using a metabolome-wide association study (MWAS) and metabolic pathway enrichment.
resultsThe serum analysis detected normal ranges of glucose, selected amino acids, fatty acids, and creatinine. Free BaP was detected in a broad concentration range. MWAS of BaP showed associations with lipids, fatty acids, and sulfur amino acid metabolic pathways.
conclusionThe results show that the DoDSR samples are of sufficient quality for chemical profiling of DoD personnel.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.