Evidence map›Paper›PMID 27501099›Full record

ArticleJournal of occupational and environmental medicine2016

Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics.

Douglas I Walker, Col Timothy M Mallon, Philip K Hopke, Karan Uppal, Young-Mi Go, Patricia Rohrbeck, Kurt D Pennell, Dean P Jones

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Occupational Exposures and Environmental Health Hazards of Military Personnel.International journal of environmental research and public health · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Environmental Chemicals Altered in Association With Deployment for High Risk Areas.Journal of occupational and environmental medicine · 2019
    Article
  15. Metabolome-Wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan.Journal of occupational and environmental medicine · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Douglas I WalkerDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia (Mr Walker, Drs Uppal, Go, Jones); Department of Civil and Environmental Engineering, Tufts University, Medford, Massachusetts (Mr Walker, Dr Pennell); Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon); Center for Air Resources Engineering and Science, Clarkson University, Potsdam, New York (Dr Hopke); and 779th Aerospace Medicine Squadron, 79th Medical Wing, Joint Base Andrews, MD (Dr Rohrbeck).
Col Timothy M Mallon
Philip K Hopke
Karan Uppal
Young-Mi Go
Patricia Rohrbeck
Kurt D Pennell
Dean P Jones

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Graduate and Postdoctoral Training in ToxicologyT32ES012870 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2004 to 2026
$9.1M
Cytoplasmic-nuclear redox signaling: Disruption by dietary cadmium levelsR01ES023485 · NIEHS · EMORY UNIVERSITY · PI GO KANG, YOUNG-MI, JONES, DEAN PAUL · 2014 to 2018
$1.8M
Orbitrap Elite/H-ESI BundleS10OD018006 · OD · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2014 to 2014
$600k
NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R01 ES023485NIEHS NIH HHS T32 ES012870NIH HHS S10 OD018006
6 · The paper itself

Abstract

objectiveThe aim of this study was to assess the suitability of high-resolution metabolomics (HRM) for measure of internal exposure and effect biomarkers from deployment-related environmental hazards.

methodsHRM provides extensive coverage of metabolism and data relevant to a broad spectrum of environmental exposures. This review briefly describes the analytic platform, workflow, and recent applications of HRM as a prototype environmental exposure surveillance system.

resultsBuilding upon techniques available for contemporary occupational medicine and exposure sciences, HRM methods are able to integrate external exposures, internal body burden of environmental agents, and relevant biological responses with health outcomes.

conclusionsSystematic analysis of existing Department of Defense Serum Repository samples will provide a high-quality, cross-sectional reference dataset for deployment-associated exposures while at the same time establishing a foundation for precision medicine.

Indexed as

MetabolomicsMilitary PersonnelBiomarkersCross-Sectional StudiesEnvironmental ExposureEnvironmental MonitoringHumansOccupational ExposureBiomarkers

Identifiers

PMID27501099
PMCPMC4978191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.