ArticleNature materials2016
Detection and imaging of quorum sensing in Pseudomonas aeruginosa biofilm communities by surface-enhanced resonance Raman scattering.
Article in Nature materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it, 345 citations in OpenAlex.
- Molecular imaging of bacterial biofilms-a systematic review.Critical reviews in microbiology · 2024Pooled it
- Time-Resolved Electrochemical Surface-Enhanced Resonance Raman Spectroscopy Double-Fingerprint for the Detection ofACS measurement science au · 2026Article
- Metasurfaces with Enhanced Optomechanical Coupling through the Colocalization of Plasmonic and Acoustic Fields.ACS nano · 2026Article
- Quantification of Antibiotic Diffusion in Biofilms Using Gold Nanostar Surface-enhanced Raman Spectroscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Understanding the development of bacterial colony: Physiology, new technology, and modeling.Quantitative biology (Beijing, China) · 2025Review
- Chiral dependence of multifunctional supramolecular materials in crop protection.Nature communications · 2025Article
- Plasmonic Polymorphs by Combining Shape Anisotropy and Soft Interactions in Bipyramid Thin Films.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Probing the Coupled Equilibria between Metal Nanoparticles, Antibiotics and Components of the Extracellular Matrix in Biofilms with SERS.Biomacromolecules · 2025Article
- Solvent-Free Ion-Conductive Xerogels with High Conductivity and Adhesion Enable Multimodal Sensing.Gels (Basel, Switzerland) · 2025Article
- Hypersaline organic wastewater treatment: Biotechnological advances and engineering challenges.Environmental science and ecotechnology · 2025Review
- Use of analytical strategies to understand spatial chemical variation in bacterial surface communities.Journal of bacteriology · 2025Review
- In vitro evaluation of biofilm formation by Streptococcus mutans and Candida albicans in orthodontic aligners.Dental press journal of orthodontics · 2025Article
- Synthesis of polypyrrole/cellulose nanocrystals disks for removal of pyocyanin metabolite biomarker released by Pseudomonas aeruginosa.PloS one · 2025Article
- Emerging advances in biosensor technologies for quorum sensing signal molecules.Analytical and bioanalytical chemistry · 2025Review
- Capturing the micro-communities: Insights into biogenesis and architecture of bacterial biofilms.BBA advances · 2025Article
- V-Shaped Heterostructure Nanocavities Array with CM and EM Coupled Enhancement for Ultra-Sensitive SERS Substrate.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Surface-Enhanced Raman Spectroscopy at the Interface between Drug Discovery and Personalized Medicine.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Review
- Article
- Review
- A multimodal nonlinear optical microscopy study of the responses of Pseudomonas aeruginosa to blue light and antibiotic treatment.Journal of biophotonics · 2024Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Funding
Abstract
Most bacteria in nature exist as biofilms, which support intercellular signalling processes such as quorum sensing (QS), a cell-to-cell communication mechanism that allows bacteria to monitor and respond to cell density and changes in the environment. As QS and biofilms are involved in the ability of bacteria to cause disease, there is a need for the development of methods for the non-invasive analysis of QS in natural bacterial populations. Here, by using surface-enhanced resonance Raman scattering spectroscopy, we report rationally designed nanostructured plasmonic substrates for the in situ, label-free detection of a QS signalling metabolite in growing Pseudomonas aeruginosa biofilms and microcolonies. The in situ, non-invasive plasmonic imaging of QS in biofilms provides a powerful analytical approach for studying intercellular communication on the basis of secreted molecules as signals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.