Evidence map›Paper›PMID 27500791›Full record

ArticleClinical pharmacology and therapeutics2016

Highlights From the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations.

P T Ronaldson, B Bauer, A F El-Kattan, H Shen, L Salphati, S W Louie

Abstract readConference Proceedings
In one paragraph

Article in Clinical pharmacology and therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

P T RonaldsonDepartment of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona, USA. pronald@email.arizona.edu.
B BauerUniversity of Kentucky, Lexington, Kentucky, USA.
A F El-KattanPfizer, Cambridge, Massachusetts, USA.
H ShenBristol-Myers Squibb, Princeton, New Jersey, USA.
L SalphatiGenentech, South San Francisco, California, USA.
S W LouieAmgen, Cambridge, Massachusetts, USA.
Amgen (United States) · USBristol-Myers Squibb (United States) · USPfizer (United States) · USUniversity of Arizona · USUniversity of Kentucky · US

Funding

Novel Therapeutic Strategies to Resolve Neurovascular Inflammation and Repair Blood-Brain Barrier Dysfunction in EpilepsyR01NS079507 · NINDS · UNIVERSITY OF MINNESOTA · PI BAUER, BJOERN · 2012 to 2025
$4.5M
Targeting Blood-Brain Barrier Transporters to Treat Ischemic StrokeR01NS084941 · NINDS · UNIVERSITY OF ARIZONA · PI RONALDSON, PATRICK THOMAS · 2014 to 2024
$4.4M
NINDS NIH HHS R01 NS079507NINDS NIH HHS R01 NS084941
6 · The paper itself

Abstract

The American Association of Pharmaceutical Scientists/International Transporter Consortium Joint Workshop on Drug Transporters in absorption, distribution, metabolism, and excretion was held with the objective of discussing innovative advances in transporter pharmacology. Specific topics included (i) transporters at the blood-brain barrier (BBB); (ii) emerging transport proteins; (iii) recent advances in achieving hepatoselectivity and optimizing clearance for organic anion-transporting polypeptide (OATP) substrates; (iv) utility of animal models for transporter studies; and (v) clinical correlation of transporter polymorphisms. Here, we present state-of-the-art highlights from this workshop in these key areas of focus.

Indexed as

Models, AnimalAnimalsBlood-Brain BarrierHumansMembrane Transport ProteinsOrganic Anion TransportersUnited StatesMembrane Transport ProteinsOrganic Anion Transporters

Identifiers

PMID27500791
PMCPMC5466066
OpenAlexW2518890417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.