ArticlePloS one2016
Genome Sequence of the Edible Cultivated Mushroom Lentinula edodes (Shiitake) Reveals Insights into Lignocellulose Degradation.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
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Who cites it
87 citing papers in PubMed.
- Genomic and Metabolomic Comparisons Provide New Insights into Plant Cell Wall Degradation, Mating Diversity and Secondary Metabolites in Brown and White CommercialInternational journal of molecular sciences · 2026Article
- High-Throughput Sequencing-Guided Development and Validation of an RT-dPCR Assay for Sensitive Detection of Lentinula edodes Spherical Virus in Shiitake Mushrooms.Current microbiology · 2026Article
- Identification of Candidate Genes Associated with the Pileus-Deficient Phenotype inJournal of fungi (Basel, Switzerland) · 2026Article
- Genomic and Transcriptomic Insights into Carbon-Source and Temporal Induction of a Diverse Set of Lignocellulolytic Enzymes inJournal of fungi (Basel, Switzerland) · 2025Article
- A high-quality genome assembly of angel-wing mushroom Pleurocybella porrigens that causes acute encephalopathy.AMB Express · 2025Article
- Cultivation methods and biology of Lentinula edodes.Applied microbiology and biotechnology · 2025Review
- Article
- The Catalytic Mechanism of Key Enzymes Involved in the Synthesis of Ergothioneine inMolecules (Basel, Switzerland) · 2024Article
- Effect of a Mating Type Gene Editing inJournal of fungi (Basel, Switzerland) · 2024Article
- Genome Sequencing ofJournal of fungi (Basel, Switzerland) · 2024Article
- Telomere-to-Telomere Haplotype-Resolved Genomes ofJournal of fungi (Basel, Switzerland) · 2024Article
- A Combination of Transcriptome and Enzyme Activity Analysis Unveils Key Genes and Patterns of Corncob Lignocellulose Degradation byJournal of fungi (Basel, Switzerland) · 2024Article
- Homologous Delta-12 Fatty Acid Desaturase (Journal of fungi (Basel, Switzerland) · 2024Article
- Transcriptome Reveals the Key Genes Related to the Metabolism of Volatile Sulfur-Containing Compounds inFoods (Basel, Switzerland) · 2024Article
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- Pleurotus ostreatus as a model mushroom in genetics, cell biology, and material sciences.Applied microbiology and biotechnology · 2024Review
- The alkynyl-containing compounds from mushrooms and their biological activities.Natural products and bioprospecting · 2023Review
- Multi-stage nuclear transcriptomic insights of morphogenesis and biparental role changes in Lentinula edodes.Applied microbiology and biotechnology · 2023Article
- Lessons on fruiting body morphogenesis from genomes and transcriptomes ofStudies in mycology · 2023Article
- Lignin-degrading enzymes from a pathogenic canker-rot fungus Inonotus obliquus strain IO-B2.AMB Express · 2023Article
27 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lentinula edodes, one of the most popular, edible mushroom species with a high content of proteins and polysaccharides as well as unique aroma, is widely cultivated in many Asian countries, especially in China, Japan and Korea. As a white rot fungus with lignocellulose degradation ability, L. edodes has the potential for application in the utilization of agriculture straw resources. Here, we report its 41.8-Mb genome, encoding 14,889 predicted genes. Through a phylogenetic analysis with model species of fungi, the evolutionary divergence time of L. edodes and Gymnopus luxurians was estimated to be 39 MYA. The carbohydrate-active enzyme genes in L. edodes were compared with those of the other 25 fungal species, and 101 lignocellulolytic enzymes were identified in L. edodes, similar to other white rot fungi. Transcriptome analysis showed that the expression of genes encoding two cellulases and 16 transcription factor was up-regulated when mycelia were cultivated for 120 minutes in cellulose medium versus glucose medium. Our results will foster a better understanding of the molecular mechanism of lignocellulose degradation and provide the basis for partial replacement of wood sawdust with agricultural wastes in L. edodes cultivation.
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