Evidence map›Paper›PMID 27500080›Full record

ArticleCurrent epidemiology reports2015

Human Papillomavirus (HPV) Infections and the Importance of HPV Vaccination.

Chia-Ching J Wang, Joel M Palefsky

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current epidemiology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chia-Ching J WangDivision of Hematology/Oncology, Helen Diller Comprehensive Cancer Center, University of California, San Francisco, 505 Parnassus Avenue, Box M1270, San Francisco, CA 94143, Telephone: 415-885-7276, , chia-ching.wang@ucsf.edu.
Joel M PalefskyDivision of Infectious Diseases, University of California, San Francisco, 513 Parnassus Ave, Med Sci Room 420E, Box 0654, San Francisco, CA 94143, Telephone: 415-476-1574, , joel.palefsky@ucsf.edu.
University of California, San Francisco · US

Funding

University of Southern CaliforniaU01CA121947 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KROWN, SUSAN E · 2006 to 2014
$54.7M
NCI NIH HHS U01 CA121947
6 · The paper itself

Abstract

HPV persistence is necessary for the development of anogenital cancer. Studies show that cervical and anal HPV infections in women and in men who have sex with men are common. Clearance of HPV infection is similarly common; few individuals show persistence unless they are HIV-infected. HIV strongly influences the development of cervical and anal cancer, as well as their pre-malignant counterparts. Women with cervical and vulvar HPV-associated lesions have higher rates of anal cancer than the general population. HPV also plays an important role in pathogenesis of head and neck cancers, particularly oropharyngeal cancer. Two commercially available HPV vaccines have been proven to be safe and efficacious against cervical HPV16/18 infections and associated precancerous lesions; one of these has also been shown to prevent HPV16/18-associated anal lesions. The FDA has also just approved a new nonavalent HPV vaccine. HPV vaccines will play an important role in prevention of HPV-associated cancers.

Indexed as

anal cancercervical cancerHIVHPVHPV vaccinationimmunosuppression

Identifiers

PMID27500080
PMCPMC4975546
OpenAlexW2061925437

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.