ReviewJournal of thoracic disease2016
Tuberculous pleural effusion.
Review in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 174 citations in OpenAlex.
- Pleural effusion aetiology, presentation, treatment and outcome in haematological diseases: a review.Acta bio-medica : Atenei Parmensis · 2021Pooled it
- Accuracy of interleukin-27 assay for the diagnosis of tuberculous pleurisy: A PRISMA-compliant meta-analysis.Medicine · 2017Pooled it
- A Study Investigating Markers in PLeural Effusion (SIMPLE): a prospective and double-blind diagnostic study.BMJ open · 2019Trial
- Predictive Ability of Sonographic Characteristics Alone to Diagnose Tuberculous Pleural Effusions in a Resource-Limited Setting: A Cross-Sectional Pilot Study in Zambia.Tropical medicine & international health : TM & IH · 2026Article
- Development of a diagnostic nomogram for tuberculous pleural effusion.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- Tuberculosis-Related Hospitalization According to Comorbidity Burden: A Retrospective Single-Center Cohort Study.Tropical medicine and infectious disease · 2026Article
- Article
- Crafty Tuberculous Pleurisy Presented With Hydropneumothorax in a 49-Year-Old Male: A Case Report.Clinical case reports · 2026Article
- Article
- Transthoracic ultrasound features to differentiate tuberculous from malignant pleural effusion: development of a machine learning-based clinical prediction model.Journal of thoracic disease · 2026Article
- Diagnostic utility of pleural fluid adenosine deaminase in tuberculous pleural effusion in patients with exudative effusion: a retrospective multicenter study (ADATPE).Journal of thoracic disease · 2026Article
- Non-invasive prediction of non-tuberculous benign pleural effusion: can we avoid unnecessary pleural biopsies?BMC pulmonary medicine · 2026Article
- Adult-Onset Primary Pleura Ewing Sarcoma With Recurrent Pleural Effusion: A Case Report and Literature Review.Respirology case reports · 2026Article
- A comprehensive diagnostic model for tuberculous PE: integration of clinical and immunological biomarkers.Frontiers in public health · 2026Article
- Role of CBNAAT and ADA in tubercular pleural effusion diagnosis at BMGMC hospital.Bioinformation · 2026Article
- The tuberculosis-associated microenvironment promotes HIV-1 persistence by impairing CD8+ T cell-mediated viral control.bioRxiv : the preprint server for biology · 2025Article
- Sarcoid Pleural Effusion Presenting With Pachypleuritis: A Rare Manifestation in a Young Adult.Cureus · 2025Article
- Unmasking Tuberculosis: A Case of Pericardial Effusion in a Young Adult With Recurrent Pneumonia.Cureus · 2025Article
- Advancing Extrapulmonary Tuberculosis Diagnosis: Potential of MPT64 Immunochemistry-Based Antigen Detection Test in a High-TB, Low-HIV Endemic Setting.Pathogens (Basel, Switzerland) · 2025Article
- Measures to accelerate recovery from stage III tuberculous empyema: tuberculous empyema surgical and recovery methods.Perioperative medicine (London, England) · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although it is curable, tuberculosis remains one of the most frequent causes of pleural effusions on a global scale, especially in developing countries. Tuberculous pleural effusion (TPE) is one of the most common forms of extrapulmonary tuberculosis. TPE usually presents as an acute illness with fever, cough and pleuritic chest pain. The pleural fluid is an exudate that usually has predominantly lymphocytes. The gold standard for the diagnosis of TPE remains the detection of Mycobacterium tuberculosis in pleural fluid, or pleural biopsy specimens, either by microscopy and/or culture, or the histological demonstration of caseating granulomas in the pleura along with acid fast bacilli, Although adenosine deaminase and interferon-γ in pleural fluid have been documented to be useful tests for the diagnosis of TPE. It can be accepted that in areas with high tuberculosis prevalence, the easiest way to establish the diagnosis of TPE in a patient with a lymphocytic pleural effusion is to generally demonstrate a adenosine deaminase level above 40 U/L. The recommended treatment for TPE is a regimen with isoniazid, rifampin, and pyrazinamide for two months followed by four months of two drugs, isoniazid and rifampin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.