ReviewThe lancet. Diabetes & endocrinology2017
The global diabetes epidemic: what does it mean for infectious diseases in tropical countries?
Review in The lancet. Diabetes & endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 9 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- Yield and Efficiency of a Population-Based Mass Tuberculosis Screening Intervention Among Persons With Diabetes in Jiangsu Province, China.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Pooled it
- Effect of Tuberculosis (TB) and Diabetes mellitus (DM) integrated healthcare on bidirectional screening and treatment outcomes among TB patients and people living with DM in developing countries: a systematic review.Pathogens and global health · 2023Pooled it
- Type 2 diabetes mellitus and antibiotic-resistant infections: a systematic review and meta-analysis.Journal of epidemiology and community health · 2022Pooled it
- Diabetes comorbidities in low- and middle-income countries: An umbrella review.Journal of global health · 2021Pooled it
- Global burden of melioidosis in 2015: a systematic review and data synthesis.The Lancet. Infectious diseases · 2019Pooled it
- The double burden of diabetes and global infection in low and middle-income countries.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2019Pooled it
- Is diabetes associated with malaria and malaria severity? A systematic review of observational studies.Wellcome open research · 2019Pooled it
- The association between diabetes/hyperglycemia and the prognosis of cervical cancer patients: A systematic review and meta-analysis.Medicine · 2017Pooled it
- [Type 2 diabetes mellitus in peru: a systematic review of prevalence and incidence in the general population].Revista peruana de medicina experimental y salud publicaPooled it
- Trial
- Increased Risk of Infections in People Living With Diabetes.Diabetes · 2026Review
- Immune dysregulation in type 2 diabetes mellitus: Implications for tuberculosis, COVID-19, and HIV/AIDS.Infectious medicine · 2025Review
- An interpretable machine learning approach to prognosis of melioidosis pneumonia via computed tomography quantification and clinical data.Scientific reports · 2025Article
- Significance of Nano Transition Metal Complexes as Anticancer and Antibacterial Therapeutic Agents.International journal of molecular sciences · 2025Article
- Triple probiotic combination effect on metabolic, oxidative stress, and inflammatory parameters in diabetic population: Systematic review and meta-analysis.World journal of experimental medicine · 2025Article
- In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone.Drug development research · 2025Article
- Unveiling the hidden effect of multi-morbidities on the severity of Covid-19: a latent class analysis approach.BMC public health · 2025Article
- Comparison Between the Impact of Diabetes Mellitus on Liver Diseases and Vice Versa Among Saudi and Egyptian Patients.Healthcare (Basel, Switzerland) · 2025Article
- Risk factors for multidrug resistance in pulmonary tuberculosis patients with diabetes mellitus.Frontiers in medicine · 2025Article
- Disruption of immune responses by type 1 diabetes exacerbates SARS-CoV-2 mediated lung injury.American journal of physiology. Lung cellular and molecular physiology · 2024Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tropical countries are experiencing a substantial rise in type 2 diabetes, which is often undiagnosed or poorly controlled. Since diabetes is a risk factor for many infectious diseases, this increase probably adds to the large infectious disease burden in tropical countries. We reviewed the literature to investigate the interface between diabetes and infections in tropical countries, including the WHO-defined neglected tropical diseases. Although solid data are sparse, patients with diabetes living in tropical countries most likely face increased risks of common and health-care-associated infections, as well as infected foot ulcers, which often lead to amputation. There is strong evidence that diabetes increases the severity of some endemic infections such as tuberculosis, melioidosis, and dengue virus infection. Some HIV and antiparasitic drugs might induce diabetes, whereas helminth infections appear to afford some protection against future diabetes. But there are no or very scarce data for most tropical infections and for possible biological mechanisms underlying associations with diabetes. The rise in diabetes and other non-communicable diseases puts a heavy toll on health systems in tropical countries. On the other hand, complications common to both diabetes and some tropical infections might provide an opportunity for shared services-for example, for eye health (trachoma and onchocerciasis), ulcer care (leprosy), or renal support (schistosomiasis). More research about the interaction of diabetes and infections in tropical countries is needed, and the infectious disease burden in these countries is another reason to step up global efforts to improve prevention and care for diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.