ArticleScientific reports2016
Developmental Validation of the Huaxia Platinum System and application in 3 main ethnic groups of China.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Systematic analysis of full-sibling identification by adding genetic markers and reference relatives.Forensic sciences research · 2025Article
- Forensic efficiency and population genetic construction of Guizhou Gelao minority from Southwest China revealed by a panel of 23 autosomal STR loci.Forensic sciences research · 2024Article
- Comprehensive analyses for genetic diversities of 19 autosomal STRs in Chinese Kazak group and its phylogenetic relationships with other continental populations.Forensic sciences research · 2022Article
- Validation of the Investigator 24plex QS Kit: a 6-dye multiplex PCR assay for forensic application in the Chinese Han population.Forensic sciences research · 2022Article
- Development and validation of novel 8-dye short tandem repeat multiplex system for forensic applications.International journal of legal medicine · 2021Article
- Developmental validation of the MGIEasy Signature Identification Library Prep Kit, an all-in-one multiplex system for forensic applications.International journal of legal medicine · 2021Article
- New insights into the fine-scale history of western-eastern admixture of the northwestern Chinese population in the Hexi Corridor via genome-wide genetic legacy.Molecular genetics and genomics : MGG · 2021Article
- Genetic polymorphism of 23 autosomal STR loci in Han population from Yuncheng, Shanxi Province.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- The Heart of Silk Road "Xinjiang," Its Genetic Portray, and Forensic Parameters Inferred From Autosomal STRs.Frontiers in genetics · 2021Article
- Forensic characteristics and phylogenetic analyses of one branch of Tai-Kadai language-speaking Hainan Hlai (Ha Hlai) via 23 autosomal STRs included in the HuaxiaMolecular genetics & genomic medicine · 2020Article
- Population genetic analysis of Shaanxi male Han Chinese population reveals genetic differentiation and homogenization of East Asians.Molecular genetics & genomic medicine · 2020Article
- Evaluation of allelic alterations in short tandem repeats in papillary thyroid cancer.Molecular genetics & genomic medicine · 2020Article
- Population genetic data from 23 autosomal STR loci of Huaxia Platinum system in the Jining Han population.Molecular genetics & genomic medicine · 2020Article
- Genetic polymorphism and phylogenetic differentiation of the Huaxia Platinum System in three Chinese minority ethnicities.Scientific reports · 2019Article
- Population Genetic Analysis of Modern and Ancient DNA Variations Yields New Insights Into the Formation, Genetic Structure, and Phylogenetic Relationship of Northern Han Chinese.Frontiers in genetics · 2019Article
- Genetic variations and forensic characteristics of Han Chinese population residing in the Pearl River Delta revealed by 23 autosomal STRs.Molecular biology reports · 2018Article
- Forensic features and phylogenetic analyses of Sichuan Han population via 23 autosomal STR loci included in the Huaxia Platinum System.International journal of legal medicine · 2018Article
- Genetic characteristics and phylogenetic analysis of three Chinese ethnic groups using the Huaxia Platinum System.Scientific reports · 2018Article
- Forensic investigation of 23 autosomal STRs and application in Han and Mongolia ethnic groups.Forensic sciences research · 2018Article
- Genetic Diversity and Phylogenetic Differentiation of Southwestern Chinese Han: a comprehensive and comparative analysis on 21 non-CODIS STRs.Scientific reports · 2017Article
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7 authors at 5 institutions in 1 country.
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Abstract
STRs, scattered throughout the genome with higher mutation rate, are attractive to genetic application like forensic, anthropological and population genetics studies. STR profiling has now been applied in various aspects of human identification in forensic investigations. This work described the developmental validation of a novel and universal assay, the Huaxia Platinum System, which amplifies all markers in the expanded CODIS core loci and the Chinese National Database in one single PCR system. Developmental validation demonstrated that this novel assay is accurate, sensitive, reproducible and robust. No discordant calls were observed between the Huaxia Platinum System and other STR systems. Full genotypes could be achieved even with 250 pg of human DNA. Additionally, 402 unrelated individuals from 3 main ethnic groups of China (Han, Uygur and Tibetan) were genotyped to investigate the effectiveness of this novel assay. The CMP were 2.3094 × 10(-27), 4.3791 × 10(-28) and 6.9118 × 10(-27), respectively, and the CPE were 0.99999999939059, 0.99999999989653 and 0.99999999976386, respectively. Aforementioned results suggested that the Huaxia Platinum System is polymorphic and informative, which provides efficient tool for national DNA database and facilitate international data sharing.
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