Evidence map›Paper›PMID 27498150›Full record

ReviewNeurochemistry international2017

Are nestin-positive mesenchymal stromal cells a better source of cells for CNS repair?

Susan L Lindsay, Susan C Barnett

Open access · hybridAbstract readReview
In one paragraph

Review in Neurochemistry international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

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  15. Generation of c-MycERScientific reports · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Susan L LindsayInstitute of Infection, Inflammation and Immunity, Glial Cell Biology Group, Sir Graeme Davies Building, Room B329, 120 University Place, University of Glasgow, Glasgow, G12 8TA, United Kingdom.
Susan C BarnettInstitute of Infection, Inflammation and Immunity, Glial Cell Biology Group, Sir Graeme Davies Building, Room B329, 120 University Place, University of Glasgow, Glasgow, G12 8TA, United Kingdom. Electronic address: Susan.Barnett@Glasgow.ac.uk.
University of Glasgow · GB

Funding

Medical Research Council MR/J004731/1
6 · The paper itself

Abstract

In recent years there has been a great deal of research within the stem cell field which has led to the definition and classification of a range of stem cells from a plethora of tissues and organs. Stem cells, by classification, are considered to be pluri- or multipotent and have both self-renewal and multi-differentiation capabilities. Presently there is a great deal of interest in stem cells isolated from both embryonic and adult tissues in the hope they hold the therapeutic key to restoring or treating damaged cells in a number of central nervous system (CNS) disorders. In this review we will discuss the role of mesenchymal stromal cells (MSCs) isolated from human olfactory mucosa, with particular emphasis on their potential role as a candidate for transplant mediated repair in the CNS. Since nestin expression defines the entire population of olfactory mucosal derived MSCs, we will compare these cells to a population of neural crest derived nestin positive population of bone marrow-MSCs.

Indexed as

AnimalsCell DifferentiationCentral Nervous System DiseasesHumansMesenchymal Stem CellsMesenchymal Stem Cell TransplantationNestinOlfactory MucosaNestinBone marrowHuman mesenchymal stromal cellsMyelinationNestinOlfactory mucosa

Identifiers

PMID27498150
PMCPMC5455984
OpenAlexW2475771913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.