Evidence map›Paper›PMID 27497945›Full record

ReviewJournal of bioenergetics and biomembranes2017

Mitochondrial Ca

Stephen Hurst, Jan Hoek, Shey-Shing Sheu

Open access · greenAbstract readReview
In one paragraph

Review in Journal of bioenergetics and biomembranes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 202 citations in OpenAlex.

  1. Review
  2. Article
  3. Mechanistic Modeling of MCUx Gatekeeping, CaAmerican journal of physiology. Cell physiology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Flavonoids fromRedox report : communications in free radical research · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Kynurenines and Mitochondrial Disturbances in Multiple Sclerosis.International journal of molecular sciences · 2025
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. GALNT9 enrichment attenuates MPPBiology direct · 2024
    Article

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stephen HurstCenter for Translational Medicine, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, 1020 Locust Street, Suite 543D, Philadelphia, PA, 19107, USA.
Jan HoekMitocare Center for Mitochondria Research, Department of Pathology Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
Shey-Shing SheuCenter for Translational Medicine, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, 1020 Locust Street, Suite 543D, Philadelphia, PA, 19107, USA. shey-shing.sheu@jefferson.edu.
Thomas Jefferson University · US

Funding

Alcohol Tissue InjuryT32AA007463 · NIAAA · THOMAS JEFFERSON UNIVERSITY · PI HOEK, JOANNES B, VADIGEPALLI, RAJANIKANTH · 1985 to 2021
$9.1M
Ethanol Effects on the Transcriptional Regulatory Network in Liver Regeneration -R01AA018873 · NIAAA · THOMAS JEFFERSON UNIVERSITY · PI SRIVASTAVA, ANKITA · 2009 to 2025
$8.7M
Ca2+ and ROS Crosstalk Signaling in Cardiac MitochondriaR01HL093671 · NHLBI · UNIVERSITY OF ROCHESTER · PI SHEU, SHEY-SHING · 2010 to 2023
$5.1M
Mitochondria-SR Tethering: Its Role in Cardiac Bioenergetics and Ca2+ DynamicsR01HL122124 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, SHEU, SHEY-SHING · 2014 to 2025
$4.0M
Vevo 2100 ultrasound scannerS10OD010408 · OD · THOMAS JEFFERSON UNIVERSITY · PI FORSBERG, FLEMMING · 2012 to 2012
$525k
NHLBI NIH HHS R01 HL093671NHLBI NIH HHS R01 HL122124NIAAA NIH HHS R01 AA018873NIAAA NIH HHS T32 AA007463NIH HHS S10 OD010408
6 · The paper itself

Abstract

The mitochondrial permeability transition pore was originally described in the 1970's as a Ca

Indexed as

AnimalsCalciumCyclophilinsHumansMembrane Potential, MitochondrialMitochondria, HeartMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PorePeptidyl-Prolyl Isomerase FProteolysisReactive Oxygen SpeciesReperfusion InjuryCalciumCyclophilinsMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PorePeptidyl-Prolyl Isomerase FReactive Oxygen SpeciesCalciumCalpainCyclophilin DGlycogen synthase kinase 3 BetaMitochondrial permeability transition poreReactive oxygen species

Identifiers

PMID27497945
PMCPMC5393273
OpenAlexW2503369629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.