Age of PISCES: stem-cell clinical trials in stroke.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Stem cell transplantation for ischemic stroke.The Cochrane database of systematic reviews · 2019
   Pooled it
2. Hydrogels with programmed spatiotemporal mechanical cues for stem cell-assisted bone regeneration.Nature communications · 2025
   Article
3. Stem cell transplantation in cerebrovascular accidents: A global bibliometric analysis (2000-2023).World journal of stem cells · 2024
   Article
4. An update on stem cell therapy for stroke patients: Where are we now?Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
   Review
5. Synergistic Therapeutic Potential of Dual 3D Mesenchymal Stem Cell Therapy in an Ischemic Hind Limb Mouse Model.International journal of molecular sciences · 2023
   Article
6. Practical Use of Immortalized Cells in Medicine: Current Advances and Future Perspectives.International journal of molecular sciences · 2023
   Review
7. Resistance to Degradation of Silk Fibroin Hydrogels Exposed to Neuroinflammatory Environments.Polymers · 2023
   Article
8. Roles of TRPV4 in Regulating Circulating Angiogenic Cells to Promote Coronary Microvascular Regeneration.Journal of cardiovascular translational research · 2023
   Article
9. Understanding neural stem cell regulationRegenerative medicine · 2021
   Review
10. Silk Fibroin: An Ancient Material for Repairing the Injured Nervous System.Pharmaceutics · 2021
    Review
11. Mitochondrial Transfer as a Therapeutic Strategy Against Ischemic Stroke.Translational stroke research · 2020
    Review
12. Stem Cell Repair of the Microvascular Damage in Stroke.Cells · 2020
    Review
13. From in vitro to in vivo reprogramming for neural transdifferentiation: An approach for CNS tissue remodeling using stem cell technology.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Review
14. Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review.World journal of stem cells · 2020
    Article
15. Bone Marrow-Derived NCS-01 Cells Advance a Novel Cell-Based Therapy for Stroke.International journal of molecular sciences · 2020
    Review
16. Concise Review: Stem Cell Therapy for Stroke Patients: Are We There Yet?Stem cells translational medicine · 2019
    Review
17. Ethical development of stem-cell-based interventions.Nature medicine · 2019
    Review
18. Cell-Based Therapies for Stroke: Are We There Yet?Frontiers in neurology · 2019
    Review
19. HDAC4 in ischemic stroke: mechanisms and therapeutic potential.Clinical epigenetics · 2018
    Review
20. Mitochondrial Dysfunction in Stroke: Implications of Stem Cell Therapy.Translational stroke research · 2018
    Review

Corrections and comments

• Comment on
  Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study.2016

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as