ArticleMedical science monitor : international medical journal of experimental and clinical research2016
Pulmonary Function in Patients with End-Stage Renal Disease: Effects of Hemodialysis and Fluid Overload.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Integrating Dialysis in Ex Situ Machine Perfusion: A Systematic Review and Meta-Analysis of Outcomes.Artificial organs · 2026Pooled it
- Effect of hemodialysis in end-stage renal disease patients on pulmonary function tests: a meta-analysis of cross-sectional studies.Frontiers in physiology · 2025Pooled it
- Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers.Chest · 2022Trial
- Dynamic changes in FGF-21 and their association with inflammation and pulmonary function in ESRD patients undergoing peritoneal dialysis: a prospective cohort study.International urology and nephrology · 2026Article
- Right ventricular-pulmonary arterial coupling and pulmonary hypertension in hemodialysis: insights into structural cardiac changes and clinical implications.Renal failure · 2025Article
- Respiratory sarcopenia screening in dialysis patients: cross-sectional and multicentre study protocol.BMC nephrology · 2024Article
- Estimation of pulmonary artery systolic pressure in hemodialysis patients and its association with cardiorespiratory fitness and pulmonary function.International urology and nephrology · 2023Article
- Lung Dysfunction and Chronic Kidney Disease: A Complex Network of Multiple Interactions.Journal of personalized medicine · 2023Review
- Rescue Everolimus Post Lung Transplantation is Not Associated With an Increased Incidence of CLAD or CLAD-Related Mortality.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- SRDA: Mobile Sensing based Fluid Overload Detection for End Stage Kidney Disease Patients using Sensor Relation Dual Autoencoder.Proceedings of machine learning research · 2023Article
- Lung-kidney interactions and their role in chronic kidney disease-associated pulmonary diseases.American journal of physiology. Lung cellular and molecular physiology · 2022Review
- A 31-year-old female patient with chronic kidney disease presenting with persistent cough.Breathe (Sheffield, England) · 2022Article
- The impact of hydration status and fluid distribution on pulmonary function in COPD patients.Scientific reports · 2022Article
- Distinguishing causation from genetic correlation in a Mendelian randomisation framework.The European respiratory journal · 2021Article
- The Pathogenesis of End-Stage Renal Disease from the Standpoint of the Theory of General Pathological Processes of Inflammation.International journal of molecular sciences · 2021Review
- Exercise intolerance in kidney diseases: physiological contributors and therapeutic strategies.American journal of physiology. Renal physiology · 2021Review
- Twelve-month effects of everolimus on renal and lung function in lung transplantation: differences in chronic lung allograft dysfunction phenotypes.Therapeutic advances in chronic disease · 2021Article
- Changes in pulmonary restrictive parameters by intensive home hemodialysis: a case report.BMC nephrology · 2020Article
- Inflammation is an amplifier of lung congestion by high lv filling pressure in hemodialysis patients: a longitudinal study.Journal of nephrology · 2020Article
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Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Respiratory system disorders are one of the most prevalent complications in end-stage renal disease patients on hemodialysis. However, the pathogenesis of impaired pulmonary functions has not been completely elucidated in these patients. We designed a study to investigate acute effects of hemodialysis treatment on spirometry parameters, focusing on the relationship between pulmonary function and fluid status in hemodialysis patients. MATERIAL AND METHODS We enrolled 54 hemodialysis patients in this study. Multifrequency bioimpedance analysis (BIA) was used to assess fluid status before and 30 min after the midweek of hemodialysis (HD). Overhydration (OH)/extracellular water (ECW)% ratio was used as an indicator of fluid status. Fluid overload was defined as OH/ECW ≥7%. Spirometry was performed before and after hemodialysis. RESULTS Forced vital capacity (FVC), FVC%, and forced expiratory volume in the first second (FEV1) levels were significantly increased after hemodialysis. FVC, FVC%, FEV1, FEV1%, mean forced expiratory flow between 25% and 75% of the FVC (FEF25-75), FEF25-75%, peak expiratory flow rate (PEFR), and PEFR% were significantly lower in patients with fluid overload than in those without. OH/ECW ratio was negatively correlated with FVC, FVC%, FEV1, FEV1%, FEF25-75, FEF25-75%, PEFR, and PEFR%. Stepwise multiple regression analysis revealed that male sex and increased ultrafiltration volume were independently associated with higher FVC, whereas increased age and OH/ECW ratio were independently associated with lower FVC. CONCLUSIONS Fluid overload is closely associated with restrictive and obstructive respiratory abnormalities in HD patients. In addition, hemodialysis has a beneficial effect on pulmonary function tests, which may be due to reduction of volume overload.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.