Evidence map›Paper›PMID 27497053›Full record

ReviewCurrent opinion in microbiology2016

Biogenesis of the Gram-positive bacterial cell envelope.

Sara D Siegel, Jun Liu, Hung Ton-That

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 60 citations in OpenAlex.

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  12. LrpCBA pilus proteins of gut-dwelling Ligilactobacillus ruminis: crystallization and X-ray diffraction analysis.Acta crystallographica. Section F, Structural biology communications · 2021
    Article
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  19. The cereus matter of Bacillus endophthalmitis.Experimental eye research · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sara D SiegelDepartment of Microbiology & Molecular Genetics, University of Texas McGovern Medical School, Houston, TX, USA.
Jun LiuDepartment of Pathology & Laboratory Medicine, University of Texas McGovern Medical School, Houston, TX, USA.
Hung Ton-ThatDepartment of Microbiology & Molecular Genetics, University of Texas McGovern Medical School, Houston, TX, USA. Electronic address: ton-that.hung@uth.tmc.edu.
The University of Texas Health Science Center at Houston · US

Funding

Molecular Assembly on the Cell Surface of ActinomycesR01DE017382 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Hung Ton-That · 2008 to 2026
$6.7M
Post-translocational protein folding in Gram-positive bacteriaR01DE025015 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TON-THAT, HUNG · 2015 to 2024
$3.9M
NIDCR NIH HHS R01 DE017382NIDCR NIH HHS R01 DE025015
6 · The paper itself

Abstract

The Gram-positive cell envelope serves as a molecular platform for surface display of capsular polysaccharides, wall teichoic acids (WTAs), lipoteichoic acids (LTAs), lipoproteins, surface proteins and pili. WTAs, LTAs, and sortase-assembled pili are a few features that make the Gram-positive cell envelope distinct from the Gram-negative counterpart. Interestingly, a set of LytR-CpsA-Psr family proteins, found in all Gram-positives but limited to a minority of Gram-negative organisms, plays divergent functions, while decorating the cell envelope with glycans. Furthermore, a phylum of Gram-positive bacteria, the actinobacteria, appear to employ oxidative protein folding as the major folding mechanism, typically occurring in an oxidizing environment of the Gram-negative periplasm. These distinctive features will be highlighted, along with recent findings in the cell envelope biogenesis.

Indexed as

ActinobacteriaCell MembraneCell WallGram-Positive BacteriaLipopolysaccharidesMembrane ProteinsPeriplasmPolysaccharidesProtein FoldingTeichoic AcidsLipopolysaccharideslipoteichoic acidMembrane ProteinsPolysaccharidesTeichoic Acids

Identifiers

PMID27497053
PMCPMC5164837
OpenAlexW2480430167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.