Trial reportClinical rehabilitation2016
Determinants of pain and functioning in knee osteoarthritis: a one-year prospective study.
Trial report in Clinical rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic Factors and Changes in Pain, Physical Functioning, and Participation in Patients With Hip and/or Knee Osteoarthritis: A Systematic Review.Arthritis care & research · 2025Pooled it
- Home-Based, Remotely Supervised Transcranial Direct Current Stimulation Improves the Overall Pain Experience of Older Adults With Knee Osteoarthritis.Pain research & management · 2025Trial
- Protection from Chronic Musculoskeletal Pain: A Scoping Review.European journal of pain (London, England) · 2026Article
- Effect of Kinesiophobia on Early Functional Outcome Following Total Knee Arthroplasty.Annals of African medicine · 2026Article
- Maladaptive Compensatory Neural Mechanisms Associated with Activity-Related Osteoarthritis Pain: Dissociation of Psychological and Activity-Related Neural Mechanisms of WOMAC Pain and VAS Pain.Journal of clinical medicine · 2025Article
- Association between widespread pain and psychosocial factors in people with knee osteoarthritis: a cross-sectional study of patients from primary care in Denmark.Physiotherapy theory and practice · 2025Article
- Validity, Reliability and Responsiveness of the Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (BETY-BQ) in Knee Osteoarthritis.Indian journal of orthopaedics · 2025Article
- Neighborhood Disadvantage and Knee Osteoarthritis Pain: Do Sleep and Catastrophizing Play a Role?Arthritis care & research · 2025Article
- Postoperative Kinesiophobia in Patients with Acute Type A Aortic Dissection: A Cross-Sectional Study.Reviews in cardiovascular medicine · 2024Article
- Understanding the biopsychosocial knee osteoarthritis pain experience: an ecological momentary assessment.Pain reports · 2024Article
- Management and Rehabilitative Treatment in Osteoarthritis with a Novel Physical Therapy Approach: A Randomized Control Study.Diagnostics (Basel, Switzerland) · 2024Article
- Pain catastrophizing in rheumatic diseases: prevalence, origin, and implications.Rheumatology international · 2024Review
- Characterization of clinical data for patient stratification in moderate osteoarthritis with support vector machines, regulatory network models, and verification against osteoarthritis Initiative data.Scientific reports · 2024Article
- Heterogeneous trajectories of kinesiophobia and their effects on rehabilitation outcomes after total knee arthroplasty: a prospective cohort study.Journal of orthopaedic surgery and research · 2023Article
- Global Research Hotspots and Trends of Physical Activity in Knee Osteoarthritis: A Bibliometric Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Resilience and recovery from total knee arthroplasty (TKA): a pathway for optimizing patient outcomes.Journal of behavioral medicine · 2022Article
- Giving an account of patients' experience: A qualitative study on the care process of hip and knee osteoarthritis.Health expectations : an international journal of public participation in health care and health policy · 2022Article
- Association of Hypertension with Knee Pain Severity Among People with Knee Osteoarthritis.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2022Article
- Does Less Pain Predict Better Quality of Life among Malaysian Patients with Mild-Moderate Knee Osteoarthritis?Clinics and practice · 2022Article
- Opioid Consumption in Chronic Pain Patients: Role of Perceived Injustice and Other Psychological and Socioeconomic Factors.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify predictors of pain and disability in knee osteoarthritis.
designA one-year prospective analysis of determinants of pain and functioning in knee osteoarthritis. STUDY
settingPrimary care providers in a medium-sized city. PATIENTS: A total of 111 patients aged from 35 to 75 with clinical symptoms and radiographic grading (Kellgren-Lawrence 2-4) of knee osteoarthritis who participated in a randomized controlled trial. MAIN MEASURES: The outcome measures were self-reported pain and function, which were recorded at 0, 3 and 12 months. Disease-specific pain and functioning were assessed using the pain and function subscales of the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index. Generic physical and mental functioning were assessed using the RAND-36 subscales for function, and physical and mental component summary scores. Possible baseline predictors for these outcomes were 1) demographic, socioeconomic and disease-related variables, and 2) psychological measures of resources, distress, fear of movement and catastrophizing.
resultsMultivariate linear mixed model analyses revealed that normal mood at baseline measured with the Beck Anxiety Inventory predicted significantly better results in all measures of pain (WOMAC P=0.02) and function (WOMAC P=0.002, RAND-36 P=0.002) during the one-year follow-up. Psychological resource factors (pain self-efficacy P=0.012, satisfaction with life P=0.002) predicted better function (RAND-36). Pain catastrophizing predicted higher WOMAC pain levels (P=0.013), whereas fear of movement (kinesiophobia) predicted poorer functioning (WOMAC P=0.046, RAND-36 P=0.024).
conclusionsMultiple psychological factors in people with knee osteoarthritis pain are associated with the development of disability and longer term worse pain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.