ArticleHearing research2016
Controlled exploration of the effects of conductive hearing loss on wideband acoustic immittance in human cadaveric preparations.
Article in Hearing research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Simulation-based inference for subject-specific tuning of middle ear finite-element models towards personalized objective diagnosis.Scientific reports · 2025Article
- Vestibular Evoked Myogenic Potentials and Wideband Acoustic Immittance as Screening Tools for Large Vestibular Aqueduct Syndrome.Journal of the American Academy of Audiology · 2025Observational
- Using Machine Learning for Analysis of Wideband Acoustic Immittance and Assessment of Middle Ear Function in Infants.Audiology research · 2025Article
- Coupled Finite Element Model of the Middle and Inner Ear as Virtual Test Environment for Stapes Surgery.International journal for numerical methods in biomedical engineering · 2025Article
- From Simulations to Inference: Using Machine Learning to Tune Patient-Specific Finite-Element Models of the Middle Ear Towards Objective Diagnosis.bioRxiv : the preprint server for biology · 2024Article
- Article
- Contemporary Mechanics of Conductive Hearing Loss.Operative techniques in otolaryngology--head and neck surgery · 2024Article
- Diagnosing Middle Ear Malformation by Pure-Tone Audiometry Using a Three-Dimensional Finite Element Model: A Case-Control Study.Journal of clinical medicine · 2023Article
- Interfacing Perforated Eardrums with Graphene-Based Membranes for Broadband Hearing Recovery.Advanced healthcare materials · 2022Article
- The influence of otitis media with effusion on middle-ear impedance estimated from wideband acoustic immittance measurements.The Journal of the Acoustical Society of America · 2021Article
- Biomechanics of Third Window Syndrome.Frontiers in neurology · 2020Review
- Effect of Middle-Ear Pathology on High-Frequency Ear Canal Reflectance Measurements in the Frequency and Time Domains.Journal of the Association for Research in Otolaryngology : JARO · 2019Article
- A Study of Wideband Energy Reflectance in Patients with Otosclerosis: Data from a Chinese Population.BioMed research international · 2019Article
- Intracochlear Sound Pressure Measurements in Normal Human Temporal Bones During Bone Conduction Stimulation.Journal of the Association for Research in Otolaryngology : JARO · 2018Article
- Identifying Otosclerosis with Aural Acoustical Tests of Absorbance, Group Delay, Acoustic Reflex Threshold, and Otoacoustic Emissions.Journal of the American Academy of Audiology · 2017Article
- Compensating for ear-canal acoustics when measuring otoacoustic emissions.The Journal of the Acoustical Society of America · 2017Article
- Effect of Cochlear Implantation on Vestibular Evoked Myogenic Potentials and Wideband Acoustic Immittance.Ear and hearingArticle
- Improving the Differential Diagnosis of Otitis Media With Effusion Using Wideband Acoustic Immittance.Ear and hearingArticle
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Current clinical practice cannot distinguish, with any degree of certainty, the multiple pathologies that produce conductive hearing loss in patients with an intact tympanic membrane and a well-aerated middle ear without exploratory surgery. The lack of an effective non-surgical diagnostic procedure leads to unnecessary surgery and limits the accuracy of information available during pre-surgical consultations with the patient. A non-invasive measurement to determine the pathology responsible for a conductive hearing loss prior to surgery would be of great value. This work investigates the utility of wideband acoustic immittance (WAI), a non-invasive measure of middle-ear mobility, in the differential diagnosis of pathologies responsible for conductive hearing loss. We focus on determining whether power reflectance (PR), a derivative of WAI, is a possible solution to this problem. PR is a measure of the fraction of sound power reflected from the middle ear when a sound stimulus is presented to the ear canal. PR and other metrics of middle-ear performance (such as ossicular motion via laser Doppler vibrometry) were measured in well-controlled human temporal bone preparations with simulated pathologies. We report measurements before and after simulation of stapes fixation (n = 8), malleus fixation (n = 10), ossicular disarticulation (n = 10), and superior canal dehiscence (n = 8). Our results are consistent with the small set of previously published reflectance measurements made in temporal bones and patients. In this present study, these temporal bone experiments with different middle- and inner-ear pathologies were compared to the initial normal state by analyzing both WAI and ossicular motion, demonstrating that WAI can be a valuable tool in the diagnosis of conductive hearing loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.