Evidence map›Paper›PMID 27496231›Full record

SynthesisBMJ open2016

Identification of adults with sepsis in the prehospital environment: a systematic review.

Michael A Smyth, Samantha J Brace-McDonnell, Gavin D Perkins

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 107 citations in OpenAlex.

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  6. Point-of-care tests in the emergency medical services: a scoping review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michael A SmythClinical Trials Unit, University of Warwick, Coventry, UK Midlands Air Ambulance, Stourbridge, UK West Midlands Ambulance Service NHS Foundation Trust, Dudley, UK.
Samantha J Brace-McDonnellClinical Trials Unit, University of Warwick, Coventry, UK Heart of England Hospital NHS Foundation Trust, Birmingham, UK.
Gavin D PerkinsClinical Trials Unit, University of Warwick, Coventry, UK Heart of England Hospital NHS Foundation Trust, Birmingham, UK.
University of Warwick · GBEast Midlands Ambulance Service NHS Trust · GB

Funding

Department of Health CDRF-2012-03-058
6 · The paper itself

Abstract

objectiveEarly identification of sepsis could enable prompt delivery of key interventions such as fluid resuscitation and antibiotic administration which, in turn, may lead to improved patient outcomes. Limited data indicate that recognition of sepsis by paramedics is often poor. We systematically reviewed the literature on prehospital sepsis screening tools to determine whether they improved sepsis recognition.

designSystematic review. The electronic databases MEDLINE, EMBASE, CINAHL, the Cochrane Library and PubMed were systematically searched up to June 2015. In addition, subject experts were contacted.

settingPrehospital/emergency medical services (EMS). STUDY SELECTION: All studies addressing identification of sepsis (including severe sepsis and septic shock) among adult patients managed by EMS. OUTCOME MEASURES: Recognition of sepsis by EMS clinicians.

resultsOwing to considerable variation in the methodological approach adopted and outcome measures reported, a narrative approach to data synthesis was adopted. Three studies addressed development of prehospital sepsis screening tools. Six studies addressed paramedic diagnosis of sepsis with or without use of a prehospital sepsis screening tool.

conclusionsRecognition of sepsis by ambulance clinicians is poor. The use of screening tools, based on the Surviving Sepsis Campaign diagnostic criteria, improves prehospital sepsis recognition. Screening tools derived from EMS data have been developed, but they have not yet been validated in clinical practice. There is a need to undertake validation studies to determine whether prehospital sepsis screening tools confer any clinical benefit.

Indexed as

Early DiagnosisEmergency Medical TechniciansAdultAmbulancesEmergency Medical ServicesFluid TherapyHumansOutcome Assessment, Health CareSepsisEMSparamedicprehospitalscreening toolsepsis

Identifiers

PMID27496231
PMCPMC4985978
OpenAlexW2486312450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.