ArticleDiabetes2016
Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet.
Article in Diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Catheter-based endovascular celiac and hepatic denervation for type 2 diabetes: a multicenter, open-label, single-arm study.Signal transduction and targeted therapy · 2025Trial
- Renal Denervation in Cardiovascular Diseases: Mechanisms, Evidence, and Expanding Applications.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Review
- Renal denervation attenuates cardiac fibrosis and improves left ventricular function in rats with myocardial infarction.Scientific reports · 2026Article
- Reframing renal denervation: from blood pressure reduction to autonomic disease modification-a state-of-the-art review.Clinical hypertension · 2026Review
- Renal interoception in health and disease.Autonomic neuroscience : basic & clinical · 2024Review
- Unravelling the effect of renal denervation on glucose homeostasis: more questions than answers?Acta diabetologica · 2024Review
- Novel regulation of renal gluconeogenesis by Atp6ap2 in response to high fat diet via PGC1-α/AKT-1 pathway.Scientific reports · 2021Article
- Renal denervation mitigates atherosclerosis in ApoE-/- mice via the suppression of inflammation.American journal of translational research · 2020Article
- Novel aspects of the role of the liver in carbohydrate metabolism.Metabolism: clinical and experimental · 2019Review
- Sympathetic Denervation of the Common Hepatic Artery Lessens Glucose Intolerance in the Fat- and Fructose-Fed Dog.Diabetes · 2019Article
- The role of kidney in the inter-organ coordination of endogenous glucose production during fasting.Molecular metabolism · 2018Article
- Electrical stimulation of renal nerves for modulating urine glucose excretion in rats.Bioelectronic medicine · 2018Article
- The Role of the Autonomic Nervous System in the Pathophysiology of Obesity.Frontiers in physiology · 2017Review
- Effects of Renal Denervation on Insulin Sensitivity and Inflammatory Markers in Nondiabetic Patients with Treatment-Resistant Hypertension.Journal of diabetes research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Activation of the sympathetic nervous system (SNS) constitutes a putative mechanism of obesity-induced insulin resistance. Thus, we hypothesized that inhibiting the SNS by using renal denervation (RDN) will improve insulin sensitivity (S
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.