ArticleMedicine2016
Therapeutic role of hyperinsulinemia/euglycemia in aluminum phosphide poisoning.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Potential role of paraffin oil gastric lavage in acute aluminum phosphide poisoning: a randomized controlled trial.Environmental science and pollution research international · 2022Trial
- Motor neuropathy following inhalational exposure to aluminum phosphide: a case report and literature review.Annals of medicine and surgery (2012) · 2026Article
- Role of serum glucose/potassium ratio in assessing poisoning severity and adverse outcomes in patients with acute aluminum phosphide poisoning.Toxicology reports · 2025Article
- Article
- Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as mortality predictors in acute Aluminum phosphide (grain pills) poisoning: clinical insights and risk assessment.Toxicology research · 2024Article
- Zinc Phosphide Poisoning: From A to Z.Toxics · 2023Review
- Treatment of critical aluminum phosphide (rice tablet) poisoning with high-dose insulin: a case report.Journal of medical case reports · 2022Article
- Hopeful News for Physicians Who Involved in the Treatment of Critical Aluminum Phosphide (Rice Pill) Poisoning Patients.Case reports in critical care · 2022Article
- Neurologic sequelae of phosphide poisoning: A case report.Frontiers in neurology · 2022Article
- Successfully managed aluminum phosphide poisoning: A case report.Annals of medicine and surgery (2012) · 2021Article
- Human Zinc Phosphide Exposure in Lebanon: A Case Report and Review of the Literature.Clinical practice and cases in emergency medicine · 2021Article
- Survival after Aluminum Phosphide Poisoning in Pregnancy.Case reports in emergency medicine · 2020Article
- Prognostic Significance of Blood Glucose Levels and Alterations Among Patients with Aluminium Phosphide Poisoning.Sultan Qaboos University medical journal · 2018Observational
- Re: Thoughts on the Current Management of Acute Aluminum Phosphide Toxicity and Proposals for Therapy: An Evidence-based Review.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2017Article
- The effect of N-acetyl cysteine (NAC) on aluminum phosphide poisoning inducing cardiovascular toxicity: a case-control study.SpringerPlus · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDifferent protocols have been suggested to treat aluminum phosphide (ALP) poisoning. We aimed to evaluate the possible therapeutic effect of hyperinsulinemia/euglycemia (HIE) in treatment of ALP poisoning.
methodsIn a prospective interventional study, a total of 88 ALP-poisoned patients were included and assigned into HIE group undergoing glucose/insulin/potassium (GIK) protocol and a control group that was managed by routine conventional treatments. The 2 groups were then compared regarding the signs and symptoms of toxicity and their progression, development of complications, and final outcome to detect the possible effect of GIK protocol on the patients' course of toxicity and outcome.
resultsThe 2 groups were similar in terms of demographic characteristics and on-arrival vital signs and lab tests. Using GIK protocol resulted in significantly longer hospital stays (24 vs 60 hours; P < 0.001) and better outcomes (72.7% vs 50% mortality; P = 0.03). Regression analysis showed that GIK duration was an independent variable that could prognosticate mortality (odds ratio [95% confidence interval] = 1.045 [1.004,1.087]). The risk of mortality decreased by 4.5% each hour after initiation of GIK.
conclusionGIK protocol improves the outcome of ALP poisoning and increases the length of hospital stay.
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