ArticleEnvironmental health perspectives2017
Perinatal Exposure to Traffic-Related Air Pollution and Autism Spectrum Disorders.
Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence of susceptibility to autism risks associated with early life ambient air pollution: A systematic review.Environmental research · 2022Pooled it
- Prenatal Exposure to Ambient Particulate Matter and Autism Spectrum Disorder in Children, a Case Control Study in France.Journal of autism and developmental disorders · 2026Observational
- The potential effects of hypothetical PM2.5 interventions on childhood autism in different neighborhood socioeconomic contexts.American journal of epidemiology · 2026Article
- Association Between Prenatal Air Pollution Exposure and Autism in Children: EPINED Study.Journal of autism and developmental disorders · 2025Article
- Exposure to Fine Particulate Matter During Pregnancy Is Associated With Hippocampal Development in Offspring.Biological psychiatry global open science · 2025Article
- Association between Prenatal Particulate Matter Exposure and Neuropsychiatric Disorders Development.Biomolecules & therapeutics · 2025Review
- Environmental factors associated with autism spectrum disorder in Southern Europe: a systematic review.International journal of developmental disabilities · 2025Review
- Independent and combined effects of fine particulate matter and greenness on autism spectrum disorder symptoms: investigating sensitive periods of exposure in the early two years of life.Frontiers in pediatrics · 2025Article
- Observational methods for human studies of transgenerational effects.Epigenetics · 2024Article
- Ultrafine particulate matter exposure during second year of life, but not before, associated with increased risk of autism spectrum disorder in BKMR mixtures model of multiple air pollutants.Environmental research · 2024Article
- The evolution of atmospheric particulate matter in an urban landscape since the Industrial Revolution.Scientific reports · 2023Article
- Air pollution exposure and social responsiveness in childhood: The cincinnati combined childhood cohorts.International journal of hygiene and environmental health · 2023Article
- The Effect of Maternal Exposure to Air Pollutants and Heavy Metals during Pregnancy on the Risk of Neurological Disorders Using the National Health Insurance Claims Data of South Korea.Medicina (Kaunas, Lithuania) · 2023Article
- Iodine Deficiency, Maternal Hypothyroxinemia and Endocrine Disrupters Affecting Fetal Brain Development: A Scoping Review.Nutrients · 2023Article
- Exposure to local, source-specific ambient air pollution during pregnancy and autism in children: a cohort study from southern Sweden.Scientific reports · 2023Article
- Prenatal exposure to ambient air pollution and autism spectrum disorders: Results from a family-based case-control study.JCPP advances · 2023Article
- Evidence of transgenerational effects on autism spectrum disorder using multigenerational space-time cluster detection.International journal of health geographics · 2022Article
- Maternal levels of acute phase proteins in early pregnancy and risk of autism spectrum disorders in offspring.Translational psychiatry · 2022Article
- Environmental exposures to pesticides, phthalates, phenols and trace elements are associated with neurodevelopment in the CHARGE study.Environment international · 2022Article
- In utero exposure to near-roadway air pollution and autism spectrum disorder in children.Environment international · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies from the United States indicate that exposure to air pollution in early life is associated with autism spectrum disorders (ASD) in children, but the evidence is not consistent with European data.
objectiveWe aimed to investigate the association between exposure to air pollution from road traffic and the risk of ASD in children, with careful adjustment for socioeconomic and other confounders.
methodChildren born and residing in Stockholm, Sweden, during 1993-2007 with an ASD diagnosis were identified through multiple health registers and classified as cases (n = 5,136). A randomly selected sample of 18,237 children from the same study base constituted controls. Levels of nitrogen oxides (NOx) and particulate matter with diameter ≤ 10 μm (PM10) from road traffic were estimated at residential addresses during mother's pregnancy and the child's first year of life by dispersion models. Odds ratios (OR) and 95% confidence intervals (CI) for ASD with or without intellectual disability (ID) were estimated using logistic regression models after conditioning on municipality and calendar year of birth as well as adjustment for potential confounders.
resultAir pollution exposure during the prenatal period was not associated with ASD overall (OR = 1.00; 95% CI: 0.86, 1.15 per 10-μg/m3 increase in PM10 and OR = 1.02; 95% CI: 0.94, 1.10 per 20-μg/m3 increase in NOx during mother's pregnancy). Similar results were seen for exposure during the first year of life, and for ASD in combination with ID. An inverse association between air pollution exposure and ASD risk was observed among children of mothers who moved to a new residence during pregnancy.
conclusionEarly-life exposure to low levels of NOx and PM10 from road traffic does not appear to increase the risk of ASD. Citation: Gong T, Dalman C, Wicks S, Dal H, Magnusson C, Lundholm C, Almqvist C, Pershagen G. 2017. Perinatal exposure to traffic-related air pollution and autism spectrum disorders. Environ Health Perspect 125:119-126; http://dx.doi.org/10.1289/EHP118.
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