Evidence map›Paper›PMID 27493936›Full record

ArticleFrontiers in public health2016

Comparative Brain and Central Nervous System Tumor Incidence and Survival between the United States and Taiwan Based on Population-Based Registry.

Li-Nien Chien, Haley Gittleman, Quinn T Ostrom, Kuo-Sheng Hung, Andrew E Sloan, Yi-Chen Hsieh, Carol Kruchko, Lisa R Rogers, Ye-Fan Glavin Wang, Hung-Yi Chiou and 1 more

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Article in Frontiers in public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Annals of nuclear medicine · 2025
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  6. The Association between p53 Expression and Histopathology Grade of Astrocytoma.Asian Pacific journal of cancer prevention : APJCP · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Li-Nien ChienCollege of Management, School of Health Care Administration, Taipei Medical University, Taipei, Taiwan; Comprehensive Cancer Center of Taipei Medical University, Taipei, Taiwan.
Haley GittlemanCase Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Central Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Quinn T OstromCase Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Central Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Kuo-Sheng HungComprehensive Cancer Center of Taipei Medical University, Taipei, Taiwan; Department of Neurosurgery, Clinical Research Center, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan; Graduate Institute of Injury Prevention and Control, Taipei Medical University, Taipei, Taiwan.
Andrew E SloanCase Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Brain Tumor and Neuro-Oncology Center, University Hospitals Case Medical Center, Cleveland, OH, USA.
Yi-Chen HsiehComprehensive Cancer Center of Taipei Medical University, Taipei, Taiwan; Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Carol KruchkoCase Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Central Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Lisa R RogersBrain Tumor and Neuro-Oncology Center, University Hospitals Case Medical Center , Cleveland, OH , USA.
Ye-Fan Glavin WangDepartment of Family Medicine and Community Health, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Taipei Medical University, Taipei, Taiwan.
Hung-Yi ChiouComprehensive Cancer Center of Taipei Medical University, Taipei, Taiwan; College of Public Health and Nutrition, School of Public Health, Taipei Medical University, Taipei, Taiwan.
Jill S Barnholtz-SloanCase Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Central Brain Tumor Registry of the United States, Hinsdale, IL, USA; Brain Tumor and Neuro-Oncology Center, University Hospitals Case Medical Center, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeReasons for worldwide variability in the burden of primary malignant brain and central nervous system (CNS) tumors remain unclear. This study compares the incidence and survival of malignant brain and CNS tumors by selected histologic types between the United States (US) and Taiwan.

methodsData from 2002 to 2010 were selected from two population-based cancer registries for primary malignant brain and CNS tumors: the Central Brain Tumor Registry of the United States and the Taiwan Cancer Registry. Two registries had similar process of collecting patients with malignant brain tumor, and the quality of two registries was comparative. The age-adjusted incidence rate (IR), IR ratio, and survival by histological types, age, and gender were used to study regional differences.

resultsThe overall age-adjusted IRs were 5.91 per 100,000 in the US and 2.68 per 100,000 in Taiwan. The most common histologic type for both countries was glioblastoma (GBM) with a 12.9% higher proportion in the US than in Taiwan. GBM had the lowest survival rate of any histology in both countries (US 1-year survival rate = 37.5%; Taiwan 1-year survival rate = 50.3%). The second largest group was astrocytoma, excluding GBM and anaplastic astrocytoma, with the distribution being slightly higher in Taiwan than in the US.

conclusionOur findings revealed differences by histological type and grade of primary malignant brain and CNS tumors between two sites.

Indexed as

CBTRUSincidencemalignant brain and central nervous system tumorssurvivalTaiwan Cancer Registry

Identifiers

PMID27493936
PMCPMC4954825

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.