Evidence map›Paper›PMID 27493903›Full record

ReviewPulse (Basel, Switzerland)2016

Molecular Mechanisms of Arterial Stiffening.

Marina Cecelja, Phil Chowienczyk

Open access · bronzeAbstract readReview
In one paragraph

Review in Pulse (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Vascular Aging and Central Aortic Blood Pressure: From Pathophysiology to Treatment.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Xuezhikang reduced arterial stiffness in patients with essential hypertension: a preliminary study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017
    Article
  13. Evaluation of aorticJRSM cardiovascular disease
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marina CeceljaKing's College London British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, UK.
Phil ChowienczykKing's College London British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, UK.
British Heart Foundation · GBKing's College London · GB

Funding

British Heart Foundation SP/12/4/29573British Heart Foundation SP/14/8/31352
6 · The paper itself

Abstract

Stiffening of large arteries is a hallmark of vascular aging and one of the most important determinants of the age-related increase in blood pressure and cardiovascular disease events. Despite a substantial genetic component, the molecular mechanisms underlying phenotypic variability in arterial stiffness remain unknown. Previous genetic studies have identified several genetic variants that are associated with measures of arterial stiffness. Here, we review the relevant advances in the identification of pathways underlying arterial stiffness from genomic studies.

Indexed as

Arterial calcificationArterial stiffeningCardiovascular diseaseGenomic studiesVascular aging

Identifiers

PMID27493903
PMCPMC4949363
OpenAlexW2407425215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.