Evidence map›Paper›PMID 27493888›Full record

ArticleEuropean thyroid journal2016

Recreational Physical Activity and Differentiated Thyroid Cancer Risk: A Pooled Analysis of Two Case-Control Studies.

Constance Xhaard, Juan J Lence-Anta, Yan Ren, Françoise Borson-Chazot, Geneviève Sassolas, Claire Schvartz, Marc Colonna, Brigitte Lacour, Arlette Danzon, Michel Velten and 21 more

Abstract read
In one paragraph

Article in European thyroid journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Trajectory of physical activity frequency and cancer risk: Findings from a population-based cohort study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023
    Article
  4. Article
  5. Physical Activity and Thyroid Cancer Risk: A Case-Control Study in Catania (South Italy).International journal of environmental research and public health · 2019
    Article
  6. Review of Factors Related to the Thyroid Cancer Epidemic.International journal of endocrinology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Constance XhaardU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Institut Gustave Roussy, Villejuif, France; Université Paris-Saclay, Villejuif, France.
Juan J Lence-AntaNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Yan RenU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Institut Gustave Roussy, Villejuif, France; Université Paris-Saclay, Villejuif, France.
Françoise Borson-ChazotGroupement Hospitalier Lyon-Est, Hospices Civils de Lyon, Fédération d'Endocrinologie, Bron, France; Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon, France.
Geneviève SassolasRhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon, France.
Claire SchvartzThyroid Cancer Registry of Champagne-Ardennes, Institut Jean Godinot, Reims, France.
Marc ColonnaCancer Registry of Isère, Meylan, France.
Brigitte LacourU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; French National Registry of Childhood Solid Tumours, CHU, Nancy, France.
Arlette DanzonCancer Registry of Doubs, EA 3181, Université de Franche-Comté, Besançon, France.
Michel VeltenCancer Registry of Bas-Rhin, EA 3430, Faculty of Medicine, University of Strasbourg, Strasbourg, France.
Enora CleroU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Institut Gustave Roussy, Villejuif, France; Université Paris-Saclay, Villejuif, France.
Stéphane MaillardU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Institut Gustave Roussy, Villejuif, France; Université Paris-Saclay, Villejuif, France.
Emilie MarrerCancer Registry of Haut-Rhin, Mulhouse Hospital, Mulhouse, France.
Laurent BaillyPublic Health Department, University Hospital Nice, Nice, France.
Eugènia Mariné BarjoanPublic Health Department, University Hospital Nice, Nice, France.
Martin SchlumbergerInstitut Gustave Roussy, Villejuif, France.
Jacques OrgiazziDepartment of Endocrinology, Hospices Civils de Lyon, Lyon, France.
Elisabeth AdjadjU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Université Paris-Saclay, Villejuif, France.
Celia M PeredaNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Silvia TurciosNational Institute of Endocrinology, Havana, Cuba.
Milagros VelascoNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Mae ChappeNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Idalmis InfanteNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Marlene BustilloNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Anabel GarcíaNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Sirced SalazarNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Regla RodriguezCuban Public Health Ministry, Havana, Cuba.
Mohamed Amine BenadjaoudU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Institut Gustave Roussy, Villejuif, France; Université Paris-Saclay, Villejuif, France.
Rosa M OrtizNational Institute of Oncology and Radiobiology (INOR), Havana, Cuba.
Carole RubinoU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Institut Gustave Roussy, Villejuif, France; Université Paris-Saclay, Villejuif, France.
Florent de VathaireU1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France; Institut Gustave Roussy, Villejuif, France; Université Paris-Saclay, Villejuif, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePhysical activity has been hypothesized to influence cancer occurrence through several mechanisms. To date, its relation with thyroid cancer risk has been examined in relatively few studies. We pooled 2 case-control studies conducted in Cuba and Eastern France to assess the relationship between self-reported practice of recreational physical activity since childhood and thyroid cancer risk.

methodsThis pooled study included 1,008 cases of differentiated thyroid cancer (DTC) matched with 1,088 controls (age range 9-35 and 17-60 years in the French and Cuban studies, respectively). Risk factors associated with the practice of recreational physical activity were estimated using OR and 95% CI. Logistic regressions were stratified by age class, country, and gender and were adjusted for ethnic group, level of education, number of pregnancies for women, height, BMI, and smoking status.

resultsOverall, the risk of thyroid cancer was slightly reduced among subjects who reported recreational physical activity (OR = 0.8; 95% CI 0.5-1.0). The weekly frequency (i.e. h/week) seems to be more relevant than the duration (years).

conclusionLong-term recreational physical activity, practiced since childhood, may reduce the DTC risk. However, the mechanisms whereby the DTC risk decreases are not yet entirely clear.

Indexed as

Pooled case-control studyRecreational physical activityRisk factorsThyroid cancer

Identifiers

PMID27493888
PMCPMC4949366

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.