ReviewBiophysics and physicobiology2015
Three-dimensional vertex model for simulating multicellular morphogenesis.
Review in Biophysics and physicobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Biophysics of lumen morphogenesis.Development (Cambridge, England) · 2026Review
- Adhesion and polarity-driven morphogenesis: Mechanisms and constraints in tissue formation.PLoS computational biology · 2026Article
- Advances in Metal Microstructure Simulation and Analysis.Materials (Basel, Switzerland) · 2026Review
- How human-derived brain organoids are built differently from brain organoids derived from genetically-close relatives: a multi-scale hypothesis.Soft matter · 2026Article
- Modeling of viscous frictional force in multicellular morphogenesis.Biophysics and physicobiology · 2026Article
- Spatially structured models of viral dynamics: a scoping review.Microbiology and molecular biology reviews : MMBR · 2025Article
- Predicting organoid morphology through a phase field model: Insights into cell division and lumenal pressure.PLoS computational biology · 2025Article
- Soft matter mechanics of immune cell aggregates.Journal of the Royal Society, Interface · 2025Article
- Studying gastrulation by invagination: The bending of a cell sheet by mechanical cell properties using 3D deformable cell based simulations.PLoS computational biology · 2025Article
- Effective mechanical potential of cell-cell interaction in tissues harboring cavity and in cell sheet toward morphogenesis.Frontiers in cell and developmental biology · 2024Article
- General, open-source vertex modeling in biological applications using Tissue Forge.Scientific reports · 2023Article
- Generative models of morphogenesis in developmental biology.Seminars in cell & developmental biology · 2023Review
- General, Open-Source Vertex Modeling in Biological Applications Using Tissue Forge.Research square · 2023Article
- Precise alternating cellular pattern in the inner ear by coordinated hopping intercalations and delaminations.Science advances · 2023Article
- Modelling of Tissue Invasion in Epithelial Monolayers.Life (Basel, Switzerland) · 2023Article
- Article
- Organoid Cultures In Silico: Tools or Toys?Bioengineering (Basel, Switzerland) · 2022Review
- Appropriate tension sensitivity of α-catenin ensures rounding morphogenesis of epithelial spheroids.Cell structure and function · 2022Article
- Seven challenges in the multiscale modeling of multicellular tissues.WIREs mechanisms of disease · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During morphogenesis, various cellular activities are spatiotemporally coordinated on the protein regulatory background to construct the complicated, three-dimensional (3D) structures of organs. Computational simulations using 3D vertex models have been the focus of efforts to approach the mechanisms underlying 3D multicellular constructions, such as dynamics of the 3D monolayer or multilayer cell sheet like epithelia as well as the 3D compacted cell aggregate, including dynamic changes in layer structures. 3D vertex models enable the quantitative simulation of multicellular morphogenesis on the basis of single-cell mechanics, with complete control of various cellular activities such as cell contraction, growth, rearrangement, division, and death. This review describes the general use of the 3D vertex model, along with its applications to several simplified problems of developmental phenomena.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.