ArticleBiophysics (Nagoya-shi, Japan)2015
Thermodynamic implications of high Q 10 of thermo-TRP channels in living cells.
Article in Biophysics (Nagoya-shi, Japan), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction.Biotechnology and bioengineering · 2026Article
- Behavioral and physiological responses of Umbonium vestiarium to temperature variation from cold-water discharge of H-OTEC system.Scientific reports · 2025Article
- Phosphorus transformations and leaching potential in rewetting drained peatlands: Exploring the influence of land use and temperature.Environmental geochemistry and health · 2025Article
- Thermal effects and ephaptic entrainment in Hodgkin-Huxley model.Scientific reports · 2024Article
- Chloride Gradient Is Involved in Ammonium Influx in Human Erythrocytes.International journal of molecular sciences · 2024Article
- Extracting thermodynamic properties from van 't Hoff plots with emphasis on temperature-sensing ion channels.Temperature (Austin, Tex.) · 2024Article
- Temperature sensitive contact modes allosterically gate TRPV3.PLoS computational biology · 2023Article
- A journey from molecule to physiology andFrontiers in pharmacology · 2023Review
- Regulation of ThermoTRP Channels by PIP2 and Cholesterol.Advances in experimental medicine and biology · 2023Article
- Platelet Hemostasis Reactions at Different Temperatures Correlate with Intracellular Calcium Concentration.International journal of molecular sciences · 2022Article
- Extracellular Enzymatic Activities of Oceanic Pelagic Fungal Strains and the Influence of Temperature.Journal of fungi (Basel, Switzerland) · 2022Article
- Profile of dorsal root ganglion neurons: study of oxytocin expression.Molecular brain · 2022Article
- Evolution of Transient Receptor Potential (TRP) Ion Channels in Antarctic Fishes (Cryonotothenioidea) and Identification of Putative Thermosensors.Genome biology and evolution · 2022Article
- Article
- Dorsolateral prefrontal cortex sensing analgesia.Biophysics and physicobiology · 2022Article
- Influence of gap junctions upon CaBiophysics and physicobiology · 2022Article
- Hydra vulgaris shows stable responses to thermal stimulation despite large changes in the number of neurons.iScience · 2021Article
- Bacterial cyclic diguanylate signaling networks sense temperature.Nature communications · 2021Article
- Lymphatic Vessels and Their Surroundings: How Local Physical Factors Affect Lymph Flow.Biology · 2020Review
- Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence.Biophysical journal · 2019Article
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3 authors.
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Abstract
The activity of thermo-transient receptor potential (TRP) channels is highly dependent on temperature, and thus thermo-TRP reactions have a high temperature coefficient Q 10. In thermodynamics, a high value of Q 10 indicates the existence of a large activation energy (i.e., a large enthalpy) over a short period during the transition process between the closed and open states of the channels. The Gibbs free energy equation shows that a large entropy is required to compensate for this large enthalpy and permit activation of the channels, suggesting a large conformational change of the channels. These large values of enthalpy and entropy seem to be a match for the values of the unfolding process of globular proteins. We outline these thermodynamic issues in thermo-TRPs.
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