Evidence map›Paper›PMID 27493460›Full record

ReviewJournal of clinical and experimental hepatology2016

Indian National Association for Study of the Liver (INASL) Guidance for Antiviral Therapy Against HCV Infection: Update 2016.

Pankaj Puri, Vivek A Saraswat, Radha K Dhiman, Anil C Anand, Subrat K Acharya, Shivaram P Singh, Yogesh K Chawla, Deepak N Amarapurkar, Ajay Kumar, Anil Arora and 15 more

Erratum issuedAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Experience with direct acting anti-viral agents for treating hepatitis C virus infection in renal transplant recipients.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017
    Article
  10. Review
  11. Article
  12. Article
  13. Hepatitis C Retreatment With First-Line Direct Acting Antiviral Drugs.Journal of clinical and experimental hepatology
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Pankaj PuriDepartment of Internal Medicine, Armed Forces Medical College, Pune 411040, India.
Vivek A SaraswatDepartment of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Radha K DhimanDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Anil C AnandDepartment of Gastroenterology and Hepatology, Indraprastha Apollo Hospital, New Delhi 110076, India.
Subrat K AcharyaDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi 110029, India.
Shivaram P SinghDepartment of Gastroenterology, SCB Medical College, Cuttack 753007, India.
Yogesh K ChawlaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Deepak N AmarapurkarDepartment of Gastroenterology, Bombay Hospital, Mumbai 400020, India.
Ajay KumarDepartment of Gastroenterology and Hepatology, Fortis Escorts Liver and Digestive Diseases Institute, New Delhi 110076, India.
Anil AroraDepartment of Gastroenterology and Hepatology, Sir Ganga Ram Hospital, New Delhi 110060, India.
Vinod K DixitDepartment of Gastroenterology, Banaras Hindu University, Varanasi 221005, India.
Abraham KoshyDepartment of Hepatology, Lakeshore Hospital, Cochin 682304, India.
Ajit SoodDepartment of Gastroenterology, Dayanand Medical College, Ludhiana 141001, India.
Ajay DusejaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Dharmesh KapoorDepartment of Gastroenterology, Global Hospital, Hyderabad 500004, India.
Kaushal MadanDepartment of Gastroenterology, Artemis Hospital, Gurgaon 122001, India.
Anshu SrivastavaDepartment of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Ashish KumarDepartment of Gastroenterology and Hepatology, Sir Ganga Ram Hospital, New Delhi 110060, India.
Manav WadhawanDepartment of Gastroenterology and Hepatology, Fortis Escorts Liver and Digestive Diseases Institute, New Delhi 110076, India.
Amit GoelDepartment of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Abhai VermaDepartment of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
ShalimarDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi 110029, India.
Gaurav PandeyDepartment of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Rohan MalikDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India.
Swastik AgrawalDepartment of Gastroenterology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

India contributes significantly to the global burden of HCV. While the nucleoside NS5B inhibitor sofosbuvir became available in the Indian market in March 2015, the other directly acting agents (DAAs), Ledipasvir and Daclatasvir, have only recently become available in the India. The introduction of these DAA in India at a relatively affordable price has led to great optimism about prospects of cure for these patients as not only will they provide higher efficacy, but combination DAAs as all-oral regimen will result in lower side effects than were seen with pegylated interferon alfa and ribavirin therapy. Availability of these newer DAAs has necessitated revision of INASL guidelines for the treatment of HCV published in 2015. Current considerations for the treatment of HCV in India include the poorer response of genotype 3, nonavailability of many of the DAAs recommended by other guidelines and the cost of therapy. The availability of combination DAA therapy has simplified therapy of HCV with decreased reliance of evaluation for monitoring viral kinetics or drug related side effects.

Indexed as

ALT, alanine aminotransferaseANC, absolute neutrophil countanti-HCV, antibody to HCVantiviral therapyAST, aspartate aminotransferaseCH-C, chronic hepatitis Cchronic hepatitisCTP, Child-Turcotte-PughDAA, directly acting antiviral agentsDCV, daclatasvirEIA, enzyme immunoassayESRD, end-stage renal diseaseEVR, early virological responseFCH, fibrosing cholestatic hepatitisGT, genotypeHCVHCV, hepatitis C virusHCWs, healthcare workershepatitis C virusHIV, human immunodeficiency virusINASL, Indian National Association for Study of the LiverIU, international unitsLDV, ledipasvirLT, liver transplantationNSI, needlestick injuryNS, nonstructural proteinPCR, polymerase chain reactionPeg-IFNα, pegylated interferon alfaRBV, ribavirinRVR, rapid virological responseSOF, sofosbuvirSVR, sustained virological responseULN, upper limit of normal

Identifiers

PMID27493460
PMCPMC4963318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.