Evidence map›Paper›PMID 27493450›Full record

ArticleMediators of inflammation2016

Evaluation of the Antioxidative, Antibacterial, and Anti-Inflammatory Effects of the Aloe Fermentation Supernatant Containing Lactobacillus plantarum HM218749.1.

Meixiu Jiang, Kan Deng, Chunling Jiang, Mingui Fu, Chunlan Guo, Xiaolei Wang, Xin Wang, Fanjing Meng, Shaoguo Yang, Keyu Deng and 2 more

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Isolation of3 Biotech · 2021
    Article
  8. Article
  9. A Clinic Trial Evaluating the Effects of Aloe Vera Fermentation Gel on Recurrent Aphthous Stomatitis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020
    Article
  10. Article
  11. Evaluation of the Treatment Effect ofMediators of inflammation · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Meixiu JiangInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.ORCID 0000-0001-8747-6877
Kan DengInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.
Chunling JiangJiangxi Cancer Hospital, Nanchang 330045, China.
Mingui FuDepartment of Basic Medical Science, School of Medicine, University of Missouri Kansas City, Kansas City, MO 64108, USA.
Chunlan GuoCollege of Forestry, Jiangxi Agriculture University, Nanchang 330045, China.
Xiaolei WangInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.
Xin WangInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.
Fanjing MengInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.
Shaoguo YangInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.
Keyu DengInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.
Tingtao ChenInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.ORCID 0000-0002-0506-8536
Hongbo XinInstitute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, China.ORCID 0000-0002-4257-207X
Nanchang University · CNJiangxi Agricultural University · CNJiangxi Provincial Cancer Hospital · CNUniversity of Missouri–Kansas City · US

Funding

Post-transcriptional Regulation of Cytokine ProductionR21AI103618 · NIAID · UNIVERSITY OF MISSOURI KANSAS CITY · PI FU, MINGUI · 2014 to 2015
$415k
NIAID NIH HHS R21 AI103618
6 · The paper itself

Abstract

Little work is done to develop Aloe vera (AV) using probiotics. To explore the potential benefits, the antioxidant effects and the antibacterial effects on foodborne pathogens of Aloe fermentation supernatant were evaluated in vitro. Our results indicated that the Aloe fermentation supernatant fermented by Lactobacillus plantarum HM218749.1 had very strong scavenging capacities of the DPPH (86%), O2 (•-) (85%), (•)OH (76%), and Fe(2+) chelation (82%) and reducing powers (242.5 mg/L), and the inhibition zones for Salmonella typhimurium, Salmonella enteritidis, Shigella flexneri, Escherichia coli, Listeria monocytogenes, S. dysenteriae 301, Staphylococcus aureus Cowan1, and Propionibacterium acnes were 16, 15, 19, 20, 21, 20, and 27 mm. Moreover, the low concentration of Aloe fermentation supernatant had significantly reduced the production of IL-1β, TNF-α, and IL-6 in both mRNA and protein levels (P < 0.01). Therefore, the Aloe fermentation supernatant can be used as functional beverage or cosmetic ingredients to guard human intestinal health, delaying senescence, and prevent chronic diseases.

Indexed as

FermentationAloeAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsEscherichia coliInterleukin-1betaInterleukin-6Lactiplantibacillus plantarumListeria monocytogenesPropionibacterium acnesSalmonella enteritidisSalmonella typhimuriumShigella flexneriStaphylococcus aureusTumor Necrosis Factor-alphaAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsInterleukin-1betaInterleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID27493450
PMCPMC4967468
OpenAlexW2504321259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.