Evidence map›Paper›PMID 27493243›Full record

ReviewJournal of leukocyte biology2016

Autophagy in leukocytes and other cells: mechanisms, subsystem organization, selectivity, and links to innate immunity.

Vojo Deretic

Open access · greenAbstract readReview
In one paragraph

Review in Journal of leukocyte biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Infectious Complications of Pulmonary Sarcoidosis.Journal of clinical medicine · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Fluorescence Spectroscopy for the Diagnosis of Endometritis in the Mare.Animals : an open access journal from MDPI · 2022
    Article
  11. Vitamin D, infections and immunity.Reviews in endocrine & metabolic disorders · 2022
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Extracellular CIRP (eCIRP) and inflammation.Journal of leukocyte biology · 2019
    Review
  18. Article
  19. The Role of Nucleic Acid Sensing in Controlling Microbial and Autoimmune Disorders.International review of cell and molecular biology · 2019
    Review
  20. Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues.American journal of physiology. Gastrointestinal and liver physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Vojo DereticDepartment of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA vderetic@salud.unm.edu.
University of New Mexico · US

Funding

Autophagy Against Tuberculosis and HIVR01AI111935 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI DERETIC, VOJO P · 2014 to 2023
$7.0M
Pattern Recognition Receptors and Autophagy in Mtb Control in AIDSR01AI042999 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI DERETIC, VOJO P · 1998 to 2017
$6.6M
Pattern Recognition Receptors and Autophagy in Mtb Control in AIDSR37AI042999 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI VOJO P DERETIC · 2018 to 2026
$4.7M
Autophagy-based HDT for tuberculosisUH2AI122313 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI DERETIC, VOJO P, ELLNER, JERROLD J. · 2015 to 2016
$1.1M
NIAID NIH HHS R01 AI042999NIAID NIH HHS R01 AI111935NIAID NIH HHS R37 AI042999NIAID NIH HHS UH2 AI122313
6 · The paper itself

Abstract

Autophagy is a fundamental biologic process that fulfills general and specialized roles in cytoplasmic homeostasis. The cell-autonomous antimicrobial functions of autophagy have been established in the macrophage. These cells and other leukocytes continue to be the cells of choice in studying autophagy in immunity and inflammation. This review uses several model examples that will be of interest to leukocyte and cell biologists alike. Furthermore, it comprehensively covers the subsystems in autophagy as they apply to all mammalian cells and incorporates the recent progress in our understanding of how these modules come together-a topic that should be of interest to all readers.

Indexed as

AutophagyImmunity, InnateAgingAnimalsGTP-Binding ProteinsHomeostasisHumansInflammationLeukocytesMammalsMiceModels, BiologicalMycobacterium tuberculosisNeoplasmsPathogen-Associated Molecular Pattern MoleculesPhagosomesGTP-Binding ProteinsIRGM protein, humanPathogen-Associated Molecular Pattern MoleculesTripartite Motif ProteinsUbiquitinATGCrohn's diseaseIRGMTRIMtuberculosis

Identifiers

PMID27493243
PMCPMC5069098
OpenAlexW2479217263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.