ReviewOral diseases2017
Fibrous dysplasia of bone: craniofacial and dental implications.
Review in Oral diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 155 citations in OpenAlex.
- Radiological and Surgical Findings of Patients with Intradiploic Mass Lesion: Case Series and Systematic Review.Journal of neurological surgery. Part A, Central European neurosurgery · 2026Pooled it
- Efficacy of antiresorptive agents in fibrous dysplasia and McCune Albright syndrome, a systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2023Pooled it
- Failure rate and treatment plan options of dental implants in patients with fibro-osseous lesions: a systematic review.Maxillofacial plastic and reconstructive surgery · 2026Review
- Imaging of Fibrous Dysplasia: A Comprehensive In-Depth Analysis of Monostotic, Polyostotic, Syndromic Forms, and Bone Sarcoma Development.Journal of imaging · 2026Review
- Article
- Management of craniofacial fibrous dysplasia: conservative or radical approach?Oral and maxillofacial surgery · 2026Article
- Bilateral Lesions Are Linked to Postoperative Regrowth in Craniofacial Fibrous Dysplasia: Alkaline Phosphatase as a Marker of Clinical Phenotype.Diagnostics (Basel, Switzerland) · 2026Article
- Polyostotic fibrous dysplasia with neuro-axial involvement: a case report and clinical insights.Acta neurologica Belgica · 2026Article
- Benign fibro-osseous lesions of the cranio-maxillofacial bones: an updated review with special emphasis on molecular pathogenesis.Journal of bone and mineral metabolism · 2026Review
- Article
- Assessment of Deep Convolutional Neural Network Models for the Classification of Benign Fibro-Osseous Lesions of the Jaws.Clinical and experimental dental research · 2025Article
- The GNAS Gene: Fibrous Dysplasia, McCune-Albright Syndrome, and Skeletal Structure and Function.Genes · 2025Review
- Craniofacial fibrous dysplasia: a challenge for general dental practitioners.British dental journal · 2025Article
- Intraosseous osteoid osteoma of the temporomandibular joint: a case report and review of the literature.BMC oral health · 2025Review
- Long-Term Follow-Up of a Patient with McCune-Albright Syndrome: A Case Report.Journal of clinical medicine · 2025Article
- Post-COVID-19 Exacerbation of a Stable Fibrous Dysplasia: A Case Report.Clinical case reports · 2025Article
- Expert consensus on imaging diagnosis and analysis of early correction of childhood malocclusion.International journal of oral science · 2025Review
- Fibrous dysplasia in the alveolar crest of edentulous site and the curettage for future implant placement: a case report.BMC oral health · 2025Article
- Late-Onset Nonhereditary Cherubism: First Reported Case in Ghana With Review of Diagnostic and Management Challenges.Case reports in radiology · 2025Article
- Rebound Hypercalcemia After Denosumab Cessation in Adult Fibrous Dysplasia: A Case Report and Clinical Alert.Case reports in endocrinology · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Fibrous dysplasia (FD) is a rare bone disease caused by postzygotic somatic activating mutations in the GNAS gene, which lead to constitutive activation of adenylyl cyclase and elevated levels of cyclic AMP, which act on downstream signaling pathways and cause normal bone to be replaced with fibrous tissue and abnormal (woven) bone. The bone disease may occur in one bone (monostotic), multiple bones (polyostotic), or in combination with hyperfunctioning endocrinopathies and hyperpigmented skin lesions (in the setting of McCune-Albright Syndrome). FD is common in the craniofacial skeleton, causing significant dysmorphic features, bone pain, and dental anomalies. This review summarizes the pathophysiology, clinical findings, and treatment of FD, with an emphasis on the craniofacial and oral manifestations of the disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.