ArticleParasite (Paris, France)2016
Prevalence of malaria, prevention measures, and main clinical features in febrile children admitted to the Franceville Regional Hospital, Gabon.
Article in Parasite (Paris, France), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Pooled it
- Reduction in total leukocytes in malaria patients compared to febrile controls: A systematic review and meta-analysis.PloS one · 2020Pooled it
- IgG antibody response against Plasmodium falciparum aminopeptidase 1 antigen in Gabonese children living in Makokou and Franceville.Clinical and experimental immunology · 2020Trial
- Hydropower development and malaria transmission: A geospatial econometric study.Journal of public health in Africa · 2025Article
- Epidemiology and diversity of Plasmodium species in Franceville and their implications for malaria control.Scientific reports · 2024Article
- Malaria Prevention for Pregnant Women and Under-Five Children in 10 Sub-Saharan Africa Countries: Socioeconomic and Temporal Inequality Analysis.International journal of environmental research and public health · 2024Article
- The role of immune-inflammatory markers in children with complicated and uncomplicated malaria in Enugu, Nigeria.BMC immunology · 2024Article
- Bayesian spatio-temporal analysis of malaria prevalence in children between 2 and 10 years of age in Gabon.Malaria journal · 2024Article
- Microscopic Malaria Infection and Its Determinants in Urban and Rural Populations Living in South-East Gabon.Journal of parasitology research · 2024Article
- Detection ofDiagnostics (Basel, Switzerland) · 2023Article
- Assessment of genetic polymorphisms associated with malaria antifolate resistance among the population of Libreville, Gabon.Malaria journal · 2023Article
- Severe malaria in children and adolescents in Southeast Gabon.BMC infectious diseases · 2023Article
- Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa.Journal of public health in Africa · 2023Article
- Severe malaria in Gabon: epidemiological, clinical and laboratory features in Amissa Bongo Hospital of Franceville.Malaria journal · 2023Article
- Epidémiology of malaria from 2019 to 2021 in the southeastern city of Franceville, Gabon.BMC public health · 2022Article
- Systematic Review on Diversity and Distribution ofPathogens (Basel, Switzerland) · 2022Review
- The primate malaria parasites Plasmodium malariae, Plasmodium brasilianum and Plasmodium ovale spp.: genomic insights into distribution, dispersal and host transitions.Malaria journal · 2022Review
- Inflammatory cytokine responses in children with asymptomatic malaria infection living in rural, semi-urban and urban areas in south-eastern Gabon.Clinical and experimental immunology · 2021Article
- Differential Prevalences ofInfection and drug resistance · 2021Article
- Malaria in children and women of childbearing age: infection prevalence, knowledge and use of malaria prevention tools in the province of Nyanga, Gabon.Malaria journal · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, major progress has been made in controlling malaria in Africa. However, in Gabon, little information is available on the role of malaria in childhood febrile syndromes, the use and efficacy of preventive measures, and Plasmodium species distribution. Here, we characterized malaria in febrile children in Franceville, Gabon through a cross-sectional study at the pediatric unit of the Franceville Regional Hospital. We registered 940 febrile children. Their general condition was markedly altered in 11.7% of cases (n = 89/760); among them 19 (21.4%) had a severely altered condition. Malaria was the second most frequent etiology (22.0%; n = 162/738), after respiratory tract infections (37.3%; n = 275/738). Children with malaria (63 ± 39 months) were older than children without malaria (40 ± 37 months) (p = 0.0013). Hemoglobin, red blood cell, white blood cell, and platelet values were lower in children with malaria than in those without malaria (p < 0.0001). Anemia was the most common feature of severe malaria (70.6%; n = 12/17), followed by neurological involvement (23.5%; n = 4/17). The prevalence of malaria was significantly higher in children older than 60 months than in younger children (40% vs. 15.5%; p < 0.0001). Plasmodium falciparum accounted for 97.5% of cases (158/162), followed by Plasmodium malariae (2.5%; n = 4/162). Bed net use was high (74.4%; n = 697/936) and contributed to malaria prevention (p = 0.001). Good basic knowledge of malaria also had a preventive effect (p < 0.0001). The prevalence of malaria in children in Franceville did not decrease significantly from 2009 to 2012, remaining at about 20%, highlighting that preventive measures should be reinforced.
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