Evidence map›Paper›PMID 27492355›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017

Non-Elective Paraesophageal Hernia Repair Portends Worse Outcomes in Comparable Patients: a Propensity-Adjusted Analysis.

Vernissia Tam, James D Luketich, Daniel G Winger, Inderpal S Sarkaria, Ryan M Levy, Neil A Christie, Omar Awais, Manisha R Shende, Katie S Nason

Abstract read
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. BRAZILIAN HERNIA AND ABDOMINAL WALL SOCIETY STATEMENT ON LARGE HIATAL HERNIAS MANAGEMENT.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Management of paraesophageal hernia review of clinical studies: timing to surgery, mesh use, fundoplication, gastropexy and other controversies.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2020
    Article
  12. Observational
  13. Article
  14. Acute Vs. Elective Paraesophageal Hernia Repair: Endoscopic Gastric Decompression Allows Semi-Elective Surgery in a Majority of Acute Patients.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
    Article
  15. Article
  16. Emergent Repair of Paraesophageal Hernias and the Argument for Elective Repair.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vernissia TamDepartment of General Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
James D LuketichDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Center Ave, Shadyside Medical Building, Suite 715, Pittsburgh, PA, 15232, USA.
Daniel G WingerUniversity of Pittsburgh Clinical and Translational Science Institute, Pittsburgh, PA, USA.
Inderpal S SarkariaDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Center Ave, Shadyside Medical Building, Suite 715, Pittsburgh, PA, 15232, USA.
Ryan M LevyDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Center Ave, Shadyside Medical Building, Suite 715, Pittsburgh, PA, 15232, USA.
Neil A ChristieDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Center Ave, Shadyside Medical Building, Suite 715, Pittsburgh, PA, 15232, USA.
Omar AwaisDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Center Ave, Shadyside Medical Building, Suite 715, Pittsburgh, PA, 15232, USA.
Manisha R ShendeDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Center Ave, Shadyside Medical Building, Suite 715, Pittsburgh, PA, 15232, USA.
Katie S NasonDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Center Ave, Shadyside Medical Building, Suite 715, Pittsburgh, PA, 15232, USA. nasonks@upmc.edu.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
Barriers to Early Detection of Esophageal AdenocarcinomaK07CA151613 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NASON, KATIE S · 2011 to 2015
$818k
NCATS NIH HHS UL1 TR000005NCI NIH HHS K07 CA151613NCI NIH HHS L30 CA179766
6 · The paper itself

Abstract

introductionPatients undergoing non-elective paraesophageal hernia repair (PEHR) have worse perioperative outcomes. Because they are usually older and sicker, however, these patients may be more prone to adverse events, independent of surgical urgency. Our study aimed to determine whether non-elective PEHR is associated with differential postoperative outcome compared to elective repair, using propensity-score weighting.

methodsWe abstracted data for patients undergoing PEHR (n = 924; non-elective n = 171 (19 %); 1997-2010). Using boosted regression, we generated a propensity-weighted dataset. Odds of 30-day/in-hospital mortality and major complications after non-elective surgery were determined.

resultsPatients undergoing non-elective repair were significantly older, had more adverse prognostic factors, and significantly more major complications (38 versus 18 %; p < 0.001) and death (8 versus 1 %; p < 0.001). After propensity weighting, median absolute percentage bias across 28 propensity-score variables improved from 19 % (significant imbalance) to 5.6 % (well-balanced). After adjusting propensity-weighted data for age and comorbidity score, odds of major complications were still nearly two times greater (OR 1.67, CI 1.07-2.61) and mortality nearly three times greater (OR 2.74, CI 0.93-8.1) than for elective repair.

conclusionsEven after balancing significant differences in baseline characteristics, non-elective PEHR was associated with worse outcomes than elective repair. Symptomatic patients should be referred for elective repair by experienced surgeons.

Indexed as

Postoperative ComplicationsAgedAged, 80 and overAge FactorsComorbidityFemaleHernia, HiatalHerniorrhaphyHospital MortalityHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesTreatment OutcomeElective surgical proceduresEmergency surgeryHiatal herniaOutcome assessmentPropensity score

Identifiers

PMID27492355
PMCPMC5209749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.