Evidence map›Paper›PMID 27492190›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2016

Arguing against the proposed definition changes of PD.

Bradley F Boeve, Dennis W Dickson, John E Duda, Tanis J Ferman, Douglas R Galasko, James E Galvin, Jennifer G Goldman, John H Growdon, Howard I Hurtig, Daniel I Kaufer and 10 more

Abstract readComment
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Where do PDD and DLB SYNdromes fit in neuronal alpha-SYNuclein biological frameworks?Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  2. Review
  3. Implications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Same, same … but different!Brain : a journal of neurology · 2023
    Article
  9. Article
  10. Lewy Body Dementias: Controversies and Drug Development.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Review
  11. Parkinson disease-associated cognitive impairment.Nature reviews. Disease primers · 2021
    Review
  12. Article
  13. Advances in dementia with Lewy bodies.Therapeutic advances in neurological disorders · 2021
    Review
  14. Article
  15. Review
  16. Pathological Influences on Clinical Heterogeneity in Lewy Body Diseases.Movement disorders : official journal of the Movement Disorder Society · 2020
    Review
  17. Review
  18. Article
  19. Article
  20. Dementia with Lewy bodies: an update and outlook.Molecular neurodegeneration · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Bradley F BoeveDepartment of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Dennis W DicksonDepartments of Pathology and Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
John E DudaDepartment of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Tanis J FermanDepartment of Psychiatry and Psychology, Mayo Clinic College of Medicine, Jacksonville, Florida, USA.
Douglas R GalaskoDepartment of Neurosciences, University of California, San Diego, California, USA.
James E GalvinMarcus Neuroscience Institute, Florida Atlantic University, Boca Raton, Florida, USA.
Jennifer G GoldmanDepartment of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.
John H GrowdonDepartment of Neurology, Harvard Medical School at Massachusetts General Hospital, Boston, Massachusetts, USA.
Howard I HurtigDepartment of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Daniel I KauferDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kejal KantarciDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
James B LeverenzLou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, Ohio, USA.
Carol F LippaDepartment of Neurology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Oscar L LopezDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ian G McKeithInstitute of Ageing, Newcastle University, Newcastle upon Tyne, UK.
Andrew B SingletonLaboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
Angela TaylorLewy Body Dementia Association, Lilburn, Georgia, USA.
Debby TsuangDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA.
Daniel WeintraubDepartment of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cyrus P ZabetianDepartment of Neurology, University of Washington School of Medicine, Seattle, Washington, USA.

Funding

THERAPEUTIC EFFECTS OF INTRA-NASAL INSULIN DETEMIRP50AG005136 · NIA · UNIVERSITY OF WASHINGTON · PI GRABOWSKI, THOMAS J. · 1985 to 2019
$57.2M
VIRUS-INDUCED BRAIN PATHOLOGYP50AG005131 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BREWER, JAMES B · 1985 to 2018
$55.4M
Genome wide SNP analysis in Parkinson's diseaseZIAAG000949 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2009 to 2024
$12.6M
Characterization of Normal Genomic VariabilityZIAAG000932 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2009 to 2024
$11.3M
Characterization of Normal Genomic VariabilityZ01AG000932 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2008 to 2008
$658k
Intramural NIH HHS Z01 AG000932NIA NIH HHS P50 AG005131NIA NIH HHS P50 AG005136
6 · The paper itself

Abstract

As members of the Lewy Body Dementia Association Scientific Advisory Council, we aim to address some of the issues raised in the article titled "Time to Redefine PD? Introductory Statement of the MDS Task Force on the Definition of Parkinson's Disease." In particular, we suggest that the 1-year rule distinguishing Parkinson's disease dementia from dementia with Lewy bodies is worth maintaining because it serves an important purpose in clinical practice and clinical and basic science research and when helping the lay community understand the complexity of these different clinical phenotypes. Furthermore, we believe that adding an additional diagnostic label, "PD (dementia with Lewy bodies subtype)," will confuse rather than clarify the distinction between dementia with Lewy bodies and PD or PD dementia, and will not improve management or expedite therapeutic development. We present arguments supporting our contentions. © 2016 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

Indexed as

DementiaLewy Body DiseaseParkinson DiseaseAdvisory CommitteesHumansPhenotypedementiaDementia with Lewy bodiesparkinsonismParkinson's disease

Identifiers

PMID27492190
PMCPMC5168716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.