ReviewReproduction (Cambridge, England)2016
Ovarian tissue transport to expand access to fertility preservation: from animals to clinical practice.
Review in Reproduction (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Transcriptome profiling of bovine preantral follicles during early folliculogenesis.Journal of animal science and biotechnology · 2026Article
- Scaffold-based biomaterials in ovarian tissue engineering.RSC advances · 2026Review
- Advancing human ovarian biology in tandem with clinical care: considerations for collecting ovarian tissue for research after oophorectomy for tissue cryopreservation.Frontiers in endocrinology · 2026Review
- Clinical outcomes over 12 years: a comparative analysis of oocyte cryopreservation from controlled ovarian stimulation and in vitro maturation retrieved from ovarian tissue.Journal of ovarian research · 2025Article
- Primordial Follicle Response to Two Methods of Ovarian Cortex Retrieval and Vitrification: A Pilot Study.Cureus · 2025Article
- Ovarian tissue cryopreservation and transplantation as a natural means to delay menopause.Archives of gynecology and obstetrics · 2024Review
- Improvement of Mouse Preantral Follicle Survival and Development following Co-Culture with Ovarian Parenchyma Cell Suspension.International journal of fertility & sterility · 2024Article
- Effects of bovine ovarian storage conditions and vitrification on isolated preantral follicle viability.Reproduction & fertility · 2024Article
- IVM Advances for Early Antral Follicle-Enclosed Oocytes Coupling Reproductive Tissue Engineering to Inductive Influences of Human Chorionic Gonadotropin and Ovarian Surface Epithelium Coculture.International journal of molecular sciences · 2023Article
- Human Ovarian Follicles Xenografted in Immunoisolating Capsules Survive Long Term Implantation in Mice.Frontiers in endocrinology · 2022Article
- High cryo-resistance of SARS-CoV-2 virus: Increased risk of re-contamination at transplantation of cryopreserved ovarian tissue after COVID-19 pandemic.Cryobiology · 2021Review
- A View from the past into our collective future: the oncofertility consortium vision statement.Journal of assisted reproduction and genetics · 2021Article
- The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.Advances in experimental medicine and biology · 2021Article
- Evidence of metabolic activity during low-temperature ovarian tissue preservation in different media.Journal of assisted reproduction and genetics · 2020Article
- Ovarian Histopathology in Transmasculine Persons on Testosterone: A Multicenter Case Series.The journal of sexual medicine · 2020Article
- Spatial Analysis of Growing Follicles in the Human Ovary to Inform Tissue Engineering Strategies.Tissue engineering. Part A · 2020Article
- Ultrasound Shear Wave Velocity Varies Across Anatomical Region inTissue engineering. Part A · 2020Article
- Tell Me Your Superpower!Endocrinology · 2020Article
- Heterotopic autotransplantation of ovarian tissue in a large animal model: Effects of cooling and VEGF.PloS one · 2020Article
- Immuno-Isolating Dual Poly(ethylene glycol) Capsule Prevents Cancer Cells from Spreading Following Mouse Ovarian Tissue Auto-Transplantation.Regenerative medicine frontiers · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Primordial follicles dictate a female's reproductive life span and therefore are central to fertility preservation for both endangered species and individuals with fertility-threatening conditions. Ovarian tissue containing primordial follicles can be cryopreserved and later thawed and transplanted back into individuals to restore both endocrine function and fertility. Importantly, increasing numbers of human live births have been reported following ovarian tissue cryopreservation and transplantation. A current limitation of this technology is patient access to sites that are approved or equipped to process and cryopreserve ovarian tissue - especially in larger countries or low resource settings. Here, we review empirical evidence from both animal models and human studies that suggest that ovarian tissue can be transported at cold temperatures for several hours while still maintaining the integrity and reproductive potential of the primordial follicles within the tissue. In fact, several human live births have been reported in European countries using tissue that was transported at cold temperatures for up to 20 h before cryopreservation and transplantation. Ovarian tissue transport, if implemented widely in clinical practice, could therefore expand both patient and provider access to emerging fertility preservation options.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.