Evidence map›Paper›PMID 27492061›Full record

ArticleNature communications2016

Long-range movement of large mechanically interlocked DNA nanostructures.

Jonathan List, Elisabeth Falgenhauer, Enzo Kopperger, Günther Pardatscher, Friedrich C Simmel

Abstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Topogami: Catenating DNA Origami.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Electrical Actuation of DNA-Based Nanomechanical Systems.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Robotic DNA Nanostructures.ACS synthetic biology · 2020
    Review
  19. DNA Origami Post-Processing by CRISPR-Cas12a.Angewandte Chemie (International ed. in English) · 2020
    Article
  20. Building machines with DNA molecules.Nature reviews. Genetics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan ListPhysik-Department E14, Technische Universität München, Am Coulombwall 4a, 85748 Garching, Germany.
Elisabeth FalgenhauerPhysik-Department E14, Technische Universität München, Am Coulombwall 4a, 85748 Garching, Germany.
Enzo KoppergerPhysik-Department E14, Technische Universität München, Am Coulombwall 4a, 85748 Garching, Germany.
Günther PardatscherPhysik-Department E14, Technische Universität München, Am Coulombwall 4a, 85748 Garching, Germany.
Friedrich C SimmelPhysik-Department E14, Technische Universität München, Am Coulombwall 4a, 85748 Garching, Germany.ORCID 0000-0003-3829-3446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interlocked molecules such as catenanes and rotaxanes, connected only via mechanical bonds have the ability to perform large-scale sliding and rotational movements, making them attractive components for the construction of artificial molecular machines and motors. We here demonstrate the realization of large, rigid rotaxane structures composed of DNA origami subunits. The structures can be easily modified to carry a molecular cargo or nanoparticles. By using multiple axle modules, rotaxane constructs are realized with axle lengths of up to 355 nm and a fuel/anti-fuel mechanism is employed to switch the rotaxanes between a mobile and a fixed state. We also create extended pseudo-rotaxanes, in which origami rings can slide along supramolecular DNA filaments over several hundreds of nanometres. The rings can be actively moved and tracked using atomic force microscopy.

Indexed as

MotionDNAFluorescenceGoldMetal NanoparticlesMicroscopy, Atomic ForceNanostructuresRotaxanesDNAGoldRotaxanes

Identifiers

PMID27492061
PMCPMC4980458

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.