ArticleEuropean radiology2017
Volumetric MRI study of the intrauterine growth restriction fetal brain.
Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Fetal brain development in fetal growth restriction using MRI: a systematic review.BMC pregnancy and childbirth · 2025Pooled it
- Evaluation of fetal brain development in growth restriction subtypes using brain MRI volume measurement.BMC pregnancy and childbirth · 2026Article
- Prenatal diffusion-weighted MRI in growth-restricted fetuses: early diffusion changes beyond Doppler findings: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- [Neuropsychological development status and risk factors in small for gestational age infants at corrected ages 12-24 months].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Assessing the impact of fetal growth restriction using high-resolution MRI: a comprehensive cortical analysis.BMC pregnancy and childbirth · 2025Article
- Cross-Modality Comparison of Fetal Brain Phenotypes: Insights From Short-Interval Second-Trimester MRI and Ultrasound Imaging.Human brain mapping · 2025Article
- Fetal MRI study of brain differences in early-onset fetal growth restriction versus healthy controls at 30 weeks of gestation.European journal of obstetrics & gynecology and reproductive biology: X · 2025Article
- Article
- An Association Between Fetal Subarachnoid Space and Various Pathologies Using MR Imaging.Diagnostics (Basel, Switzerland) · 2024Article
- Real-time fetal brain tracking for functional fetal MRI.Magnetic resonance in medicine · 2023Article
- Impact of early-onset fetal growth restriction on the neurodevelopmental outcome of very preterm infants at 24 months: a retrospective cohort study.BMC pediatrics · 2023Article
- Sexual dimorphism of the fetal brain biometry: an MRI-based study.Archives of gynecology and obstetrics · 2023Article
- Subarachnoid Space Measurements in Apparently Healthy Fetuses Using MR Imaging.AJNR. American journal of neuroradiology · 2023Article
- Cranial Ultrasound Abnormalities in Small for Gestational Age or Growth-Restricted Infants Born over 32 Weeks Gestation: A Systematic Review and Meta-Analysis.Brain sciences · 2022Review
- Molecular Indicators of Blood-Brain Barrier Breakdown and Neuronal Injury in Pregnancy Complicated by Fetal Growth Restriction.International journal of molecular sciences · 2022Article
- Volumetric Brain MRI Study in Fetuses with Intrauterine Growth Restriction Using a Semiautomated Method.AJNR. American journal of neuroradiology · 2022Article
- Association of Corpus Callosum Development With Fetal Growth Restriction and Maternal Preeclampsia or Gestational Hypertension.JAMA network open · 2022Article
- Correlation between 2D and 3D Fetal Brain MRI Biometry and Neurodevelopmental Outcomes in Fetuses with Suspected Microcephaly and Macrocephaly.AJNR. American journal of neuroradiology · 2021Article
- Twin discordance: a study of volumetric fetal brain MRI and neurodevelopmental outcome.European radiology · 2021Article
- Cardiac magnetic resonance imaging: insights into developmental programming and its consequences for aging.Journal of developmental origins of health and disease · 2021Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIntrauterine growth restriction (IUGR) is a pathologic fetal condition known to affect the fetal brain regionally and associated with future neurodevelopmental abnormalities. This study employed MRI to assess in utero regional brain volume changes in IUGR fetuses compared to controls.
methodsRetrospectively, using MRI images of fetuses at 30-34 weeks gestational age, a total of 8 brain regions-supratentorial brain and cavity, cerebral hemispheres, temporal lobes and cerebellum-were measured for volume in 13 fetuses with IUGR due to placental insufficiency and in 21 controls. Volumes and their ratios were assessed for difference using regression models. Reliability was assessed by intraclass correlation coefficients (ICC) between two observers.
resultsIn both groups, all structures increase in absolute volume during that gestation period, and the rate of cerebellar growth is higher compared to that of supratentorial structures. All structures' absolute volumes were significantly smaller for the IUGR group. Cerebellar to supratentorial ratios were found to be significantly smaller (P < 0.05) for IUGR compared to controls. No other significant ratio differences were found. ICC showed excellent agreement.
conclusionsThe cerebellar to supratentorial volume ratio is affected in IUGR fetuses. Additional research is needed to assess this as a radiologic marker in relation to long-term outcome. KEY POINTS: • IUGR is a pathologic fetal condition affecting the brain • IUGR is associated with long-term neurodevelopmental abnormalities; fetal characterization is needed • This study aimed to evaluate regional brain volume differences in IUGR • Cerebellar to supratentorial volume ratios were smaller in IUGR fetuses • This finding may play a role in long-term development of IUGR fetuses.
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