ArticleBMC ophthalmology2016
Visualization of precut DSAEK and pre-stripped DMEK donor corneas by intraoperative optical coherence tomography using the RESCAN 700.
Article in BMC ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 24 citations in OpenAlex.
- Intraoperative OCT for Lamellar Corneal Surgery: A User Guide.Journal of clinical medicine · 2023Review
- The predictability of graft thickness for Descemet's stripping automated endothelial keratoplasty using a mechanical microkeratome system.Scientific reports · 2022Article
- Intraoperative optical coherence tomography-guided donor corneal tissue assessment and preparation.Indian journal of ophthalmology · 2022Article
- An Overview of Intraoperative OCT-Assisted Lamellar Corneal Transplants: A Game Changer?Diagnostics (Basel, Switzerland) · 2022Review
- Correlation between intraoperative and postoperative vaulting of the EVO implantable Collamer lens: a retrospective study of real-time observations of vaulting using the RESCAN 700 system.BMC ophthalmology · 2022Article
- Application of Intraoperative Optical Coherence Tomography Technology in Anterior Segment Surgery.Journal of ophthalmology · 2022Review
- Comprehensive review of surgical microscopes: technology development and medical applications.Journal of biomedical optics · 2021Review
- What Is the Impact of Intraoperative Microscope-Integrated OCT in Ophthalmic Surgery? Relevant Applications and Outcomes. A Systematic Review.Journal of clinical medicine · 2020Review
- Intraoperative Optical Coherence Tomography Imaging in Corneal Surgery: A Literature Review and Proposal of Novel Applications.Journal of ophthalmology · 2020Article
- Observation of Gonio Structures during Microhook Ab Interno Trabeculotomy Using a Novel Digital Microscope with Integrated Intraoperative Optical Coherence Tomography.Journal of ophthalmology · 2020Article
- Intraoperative Optical Coherence Tomography Guided Ocular Surgeries: Critical Analysis of Clinical Role and Future Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
- Intraoperative optical coherence tomography in anterior segment surgeries.Indian journal of ophthalmology · 2017Review
- Optical Coherence Tomography Observation of Gonio Structures during Microhook Ab Interno Trabeculotomy.Journal of ophthalmology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo report the feasibility of intraoperative spectral domain optical coherence tomography (OCT) using the RESCAN 700 for the visualization and evaluation of precut Descemet's stripping automated endothelial keratoplasty (DSAEK) and prestripped Descemet's membrane endothelial keratoplasty (DMEK) donor tissue.
methodsPrecut DSAEK (n = 11), prestripped DMEK (n = 4) preserved in a viewing chamber were examined by intraoperative OCT. Wholly intact donor corneas for penetrating keratoplasty (PK) (n = 8) were also examined as controls. The obtained images were analyzed qualitatively for characteristics of each type of donor.
resultsFor each type of donor, characteristic images were consistently obtained by intraoperative OCT in both the front and back views through the viewing chamber. In wholly intact donors for PK, appearance of normal corneal curvature and stromal texture with high reflectivity of epithelium and endothelium cell layers were clearly visualized. In precut DSAEK donors, precut lines were characteristically visualized in addition to the intact donor cornea images. In prestripped DMEK donors, identical OCT images to the intact donor cornea were noted when observed from the anterior surface. However, peripheral partial detachments of Descemet's membrane were characteristically observed in all prestripped DMEK donors when viewed from the back of the viewing chamber.
conclusionRapid visualization and rough evaluation of donor tissues for PK, precut DSAEK and prestripped DMEK donor corneas by intraoperative OCT was consistently possible through the viewing chamber. Therefore, this device may be used as an alternative of AS-OCT when the eyebank does not have their own AS-OCT. Although the peripheral detachment in DMEK donors are quite common and clinically non-problematic in DMEK donor quality and subsequent DMEK surgeries, it may be useful to distinguish between wholly intact PK donors and prestripped DMEK donors, enabling to prevent mix-ups of donors, especially when several different types of keratoplasties are scheduled in a same day in one operating theater.
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