ReviewPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2016
Neurodevelopmental Outcomes in Children With Congenital Heart Disease-What Can We Impact?
Review in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
102 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Causal inference between neurodevelopmental disorders and brain structure among individuals with congenital heart disease: Insights from meta-analysis and Mendelian randomization.Italian journal of pediatrics · 2026Pooled it
- Neurosonographic Evaluation of Cerebral Cortical Development in Fetuses With Congenital Heart Disease: A Systematic Review of the Literature.Prenatal diagnosis · 2025Pooled it
- The Association Between Congenital Heart Disease and Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.Pediatric cardiology · 2023Pooled it
- Developmental Care in the Early Years in Pediatric Intensive Care Patients as a Strategy to Mitigate Pediatric Post-Intensive-Care Syndrome: A Narrative Review.Journal of intensive care medicine · 2026Review
- Opioid and Methadone Prescribing for Infants with Surgical Management of Congenital Heart Disease.Pediatric cardiology · 2026Observational
- Neurocognitive and Socio-Emotional Profile of Children with 22q11.2 Deletion Syndrome: Executive Functions, Social Processing Deficits and Clinical Implications.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026Review
- Parental Experiences and Psychological Support Needs Following Fetal Diagnosis of Congenital Heart Disease: A Qualitative Study.Pediatric cardiology · 2026Article
- Surgical Timing, Preoperative Oxygenation, and Sex Are Associated with Oxidative Stress and αMedical sciences (Basel, Switzerland) · 2026Article
- Connection after correction: Parent-child relationships following early cardiac surgery.Infant mental health journal · 2026Article
- Neurodevelopmental care across pediatric critical care settings: toward brain-focused critical care.European journal of pediatrics · 2026Review
- Psychological Aspects and Mental Health Risks in Children and Adolescents with Congenital Heart Defects-A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Prenatal maternal psychological distress is associated with neurodevelopmental outcomes in toddlers with congenital heart disease.Pediatric research · 2026Article
- Neurodevelopment Among Publicly Insured Children in the First 5 Years After Infant Heart Surgery.JAMA network open · 2026Article
- Psychomotor Development in Pediatric Patients with Congenital Heart Defects Prior to Surgical Intervention: Findings from a Prospective Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Preoperative Oral Feeding in Infants with Congenital Heart Disease Within the First Month of Life is Associated with a Higher Likelihood of Freedom From Tube Feeding at Time of Postoperative Discharge.Pediatric cardiology · 2026Observational
- Perioperative mortality and 1-year neurodevelopmental outcome after cardiac surgery prior to 6 weeks of age, requiring perioperative extracorporeal membrane oxygenation in the first year of life.Frontiers in cardiovascular medicine · 2026Article
- Characterizing neurodevelopmental follow-up attendance of children with congenital heart disease.Pediatric research · 2026Article
- Shear wave elastography assessment of periventricular white matter and thalamic stiffness changes in infants with congenital heart disease undergoing cardiac surgery.Frontiers in medicine · 2026Article
- Review
- Addressing Survivorship Bias in Neurocognitive Outcomes After Early Complex Cardiac Surgery Using Clustering and Propensity Scores.CJC pediatric and congenital heart disease · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectivesThe objectives of this review are to discuss the scope of neurologic injuries in newborns with congenital heart disease, the mechanisms of injury, including prenatal, pre-, intra-, and postoperative factors, neurodevelopmental outcomes, and therapeutic strategies for the timely intervention and prevention of neurologic injury. DATA SOURCE: MEDLINE and PubMed.
conclusionAt the current time, important research is underway to 1) better understand the developing brain in the fetus with complex congenital heart disease, 2) to identify modifiable risk factors in the operating room and ICU to maximize long-term neurodevelopmental outcomes, and 3) develop strategies to improve family psychosocial health, childhood development, and health-related quality of life following hospital discharge. Crucial in this effort is the identification of an early postoperative surrogate variable with good predictive validity for long-term outcomes. If an appropriate surrogate variable for long-term outcomes can be identified, and measured relatively early after surgical intervention for complex congenital heart disease, reliable clinical trials can be undertaken to improve upon current outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.