Evidence map›Paper›PMID 27490477›Full record

ArticlePloS one2016

Impact of Health System Inputs on Health Outcome: A Multilevel Longitudinal Analysis of Botswana National Antiretroviral Program (2002-2013).

Mansoor Farahani, Natalie Price, Shenaaz El-Halabi, Naledi Mlaudzi, Koona Keapoletswe, Refeletswe Lebelonyane, Ernest Benny Fetogang, Tony Chebani, Poloko Kebaabetswe, Tiny Masupe and 4 more

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mansoor FarahaniHarvard T.H. Chan School of Public Health, Boston, MA, United States of America.ORCID http://orcid.org/0000-0002-8968-9822
Natalie PriceHarvard T.H. Chan School of Public Health, Boston, MA, United States of America.
Shenaaz El-HalabiMinistry of Health, Gaborone, Botswana.
Naledi MlaudziMinistry of Health, Gaborone, Botswana.
Koona KeapoletsweMinistry of Health, Gaborone, Botswana.
Refeletswe LebelonyaneMinistry of Health, Gaborone, Botswana.
Ernest Benny FetogangMinistry of Health, Gaborone, Botswana.
Tony ChebaniHarvard T.H. Chan School of Public Health, Boston, MA, United States of America.
Poloko KebaabetsweUniversity of Botswana, Gaborone, Botswana.
Tiny MasupeUniversity of Botswana, Gaborone, Botswana.
Keba GabaakeUniversity of Botswana, Gaborone, Botswana.
Andrew F AuldDivision of Global HIV/AIDS, Center for Global Health, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Oathokwa NkomazanaUniversity of Botswana, Gaborone, Botswana.
Richard MarlinkHarvard T.H. Chan School of Public Health, Boston, MA, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo measure the association between the number of doctors, nurses and hospital beds per 10,000 people and individual HIV-infected patient outcomes in Botswana.

designAnalysis of routinely collected longitudinal data from 97,627 patients who received ART through the Botswana National HIV/AIDS Treatment Program across all 24 health districts from 2002 to 2013. Doctors, nurses, and hospital bed density data at district-level were collected from various sources.

methodsA multilevel, longitudinal analysis method was used to analyze the data at both patient- and district-level simultaneously to measure the impact of the health system input at district-level on probability of death or loss-to-follow-up (LTFU) at the individual level. A marginal structural model was used to account for LTFU over time.

resultsIncreasing doctor density from one doctor to two doctors per 10,000 population decreased the predicted probability of death for each patient by 27%. Nurse density changes from 20 nurses to 25 nurses decreased the predicted probability of death by 28%. Nine percent decrease was noted in predicted mortality of an individual in the Masa program for every five hospital bed density increase.

conclusionConsiderable variation was observed in doctors, nurses, and hospital bed density across health districts. Predictive margins of mortality and LTFU were inversely correlated with doctor, nurse and hospital bed density. The doctor density had much greater impact than nurse or bed density on mortality or LTFU of individual patients. While long-term investment in training more healthcare professionals should be made, redistribution of available doctors and nurses can be a feasible solution in the short term.

Indexed as

Program EvaluationAdultAnti-HIV AgentsBotswanaDelivery of Health CareFemaleHealth FacilitiesHIV InfectionsHumansLogistic ModelsLongitudinal StudiesLost to Follow-UpMaleMiddle AgedNursesOdds RatioAnti-HIV Agents

Identifiers

PMID27490477
PMCPMC4974006

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.