Evidence map›Paper›PMID 27490002›Full record

ArticleHearing research2016

Motion of tympanic membrane in guinea pig otitis media model measured by scanning laser Doppler vibrometry.

Xuelin Wang, Xiying Guan, Mario Pineda, Rong Z Gan

Abstract read
In one paragraph

Article in Hearing research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Mammalian middle ear mechanics: A review.Frontiers in bioengineering and biotechnology · 2022
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Panel 7 - Pathogenesis of otitis media - a review of the literature between 2015 and 2019.International journal of pediatric otorhinolaryngology · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Surface Motion of Tympanic Membrane in a Chinchilla Model of Acute Otitis Media.Journal of the Association for Research in Otolaryngology : JARO · 2018
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xuelin WangSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, Norman, OK, USA.
Xiying GuanSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, Norman, OK, USA.
Mario PinedaPolytec Inc., Irvine, CA, USA.
Rong Z GanSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, Norman, OK, USA. Electronic address: rgan@ou.edu.
University of Oklahoma · US

Funding

Biomechanical Measurement and Modeling of Normal and Diseased Middle EarsR01DC011585 · NIDCD · UNIVERSITY OF OKLAHOMA · PI GAN, RONG Z · 2011 to 2015
$1.7M
NIDCD NIH HHS R01 DC011585
6 · The paper itself

Abstract

Otitis media (OM) is an inflammatory or infectious disease of the middle ear. Acute otitis media (AOM) and otitis media with effusion (OME) are the two major types of OM. However, the tympanic membrane (TM) motion differences induced by AOM and OME have not been quantified in animal models in the literature. In this study, the guinea pig AOM and OME models were created by transbullar injection of Streptococcus pneumoniae type 3 and lipopolysaccharide, respectively. To explore the effects of OM on the entire TM vibration, the measurements of full-field TM motions were performed in the AOM, OME and untreated control ears by using scanning laser Doppler vibrometry (SLDV). The results showed that both AOM and OME generally reduced the displacement peak and produced the traveling-wave-like motions at relatively low frequencies. Compared with the normal ear, OME resulted in a significant change of the TM displacement mainly in the inferior portion of the TM, and AOM significantly affected the surface motion across four quadrants. The SLDV measurements provide more insight into sound-induced TM vibration in diseased ears.

Indexed as

AnimalsDisease Models, AnimalEar, MiddleGuinea PigsLaser-Doppler FlowmetryLipopolysaccharidesMotionOtitis MediaOtitis Media with EffusionTympanic MembraneVibrationLipopolysaccharidesAcute otitis mediaMiddle earOtitis media with effusionTympanic membrane

Identifiers

PMID27490002
PMCPMC5018450
OpenAlexW2483155149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.