Evidence map›Paper›PMID 27489867›Full record

ArticleEuropean journal of radiology open2016

Diffusion-weighted MR imaging of non-complicated hepatic cysts: Value of 3T computed diffusion-weighted imaging.

Yuko Nakamura, Toru Higaki, Yuji Akiyama, Wataru Fukumoto, Kenji Kajiwara, Yoko Kaichi, Yukiko Honda, Daisuke Komoto, Fuminari Tatsugami, Makoto Iida and 3 more

Open access · goldAbstract read
In one paragraph

Article in European journal of radiology open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Use of a b-Value of 3000 s/mmJuntendo medical journal · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Yuko NakamuraDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Toru HigakiDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Yuji AkiyamaDepartment of Radiology, Hiroshima University Hospital, Hiroshima, Japan.
Wataru FukumotoDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Kenji KajiwaraDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Yoko KaichiDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Yukiko HondaDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Daisuke KomotoDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Fuminari TatsugamiDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Makoto IidaDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Toshifumi OhmotoRadiology, Kure City Medical Association Hospital, Kure, Japan.
Shuji DateDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Kazuo AwaiDiagnostic Radiology, Hiroshima University, Hiroshima, Japan.
Hiroshima University · JPHiroshima University Hospital · JPKure Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the utility of computed 3T diffusion-weighted imaging (c-DWI) for the diagnosis of non-complicated hepatic cysts with a focus on the T2 shine-through effect. MATERIALS AND

methodsIn 50 patients with non-complicated hepatic cysts we acquired one set of DWIs (b-value 0 and 1000 s/mm(2)) at 1.5T, and two sets at 3T (b-value 0 and 1000 s/mm(2), TE 70 ms; b-value 0 and 600 s/mm(2), TE 60 ms). We defined the original DWIs acquired with b = 1000 s/mm(2) at 1.5T and 3T as "o-1.5T-1000" and "o-3T-1000". c-DWIs were calculated with 3T DWI at b-values of 0 and 600 s/mm(2). c-DWI with b = 1000 and 1500 s/mm(2) were defined as "c-1000" and "c-1500". Radiologists evaluated the signal intensity (SI) of the cysts using a 3-point score where 1 = not visible, 2 = discernible, and 3 = clearly visible. They calculated the contrast ratio (CR) between the cysts and the surrounding liver parenchyma on each DWIs and recorded the apparent diffusion coefficient (ADC) with a b-value = 0 and 1000 s/mm(2) on 1.5T- and 3T DWIs.

resultsCompared with o-1.5T-1000 DWI, the visual scores of all but the c-1500 DWIs were higher (p = 0.07 for c-1500- and p < 0.01 for the other DWIs). The CR at b = 1000 s/mm(2) was higher on o-3T-1000- than on o-1.5T-1000- (p < 0.01) but not higher than on c-1500 DWIs (p = 0.96). The CR at b = 0 s/mm(2) on 3T images with TE 70 ms was higher than on 1.5T images (p < 0.01). The ADC value was higher for 3T- than 1.5T images (p < 0.01).

conclusionsNon-complicated hepatic cysts showed higher SI on o-3T-1000- than o-1.5T-1000 DWIs due to the T2-shine through effect. This high SI was suppressed on c-1500 DWIs.

Indexed as

ADC, apparent diffusion coefficientc-DWI, computed diffusion-weighted imagingComputed diffusion-weighted imagingCR, contrast ratioDiffusion-weighted imagingDWI, diffusion-weighted imagingField strengthHCC, hepatocellular carcinomaMRI, magnetic resonance imagingNon-complicated hepatic cystsSI, signal intensitySNR, signal-to-noise ratioT1-WI, T1-weighted MRIT2 shine-through effectT2-WI, T2-weighted MRI

Identifiers

PMID27489867
PMCPMC4959945
OpenAlexW2483437049

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.